An observational study in Stroke and Cognitive Decline, sponsored by Dingqun Bai. Recruiting at 1 site in China. Open to participants aged 18 Years to 80 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-11-26.
Sponsored by Dingqun Bai · Observational
This is an fNIRS study performed to identify biomarkers related to post-stroke cognitive impairment.
This was an initial screening and preliminary intervention study. Both healthy subject and stroke patients will be included in this study. Brain functional activation of each subject during the cognitive task (Stroop task, 1-back task and verbal fluency test) will be evaluated using functional near-infrared spectroscopy (fNIRS). Cognitive function related scale assessment included Mental State Examination Scale (MMSE), Montreal Cognitive Assessment (MoCA), drawing clock test (DCT), Shape trials test A.B (STT-A, STT-B), standardized digital modal test (SDMT), auditory verbal learning test-Huashan version (AVLT-H), and activity of daily living (ADL) scale will be used to evaluate the function of each patient. Biomarkers related to post-stroke cognitive impairment will be identified by by comparing differences in brain activation and brain network connectivity between patients and healthy subjects.
7,286 studies on the registry are indexed under Stroke; 2,013 are open to participants now.
This study's planned enrollment of 60 is below the median of 160 across 1,692 observational studies indexed under Stroke.
Browse Stroke studies →Dingqun Bai is the lead sponsor of 4 studies on the registry; 3 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients with stroke in the inpatient ward of the Department of Rehabilitation Medicine, The First Affiliated Hospital of Chongqing Medical University.
Healthy subjects recruited through the Department of Rehabilitation Medicine, The First Affiliated Hospital of Chongqing Medical University.
Stroke patients:
Healthy Subjects:
Exclusion Criteria:
Stroke patients:
Healthy Subjects:
Healthy subjects without history of stroke or cognitive impairment.
Stroke patients with post-stroke cognitive impairment.
Stroke patients without post-stroke cognitive impairment.
Preliminary screening of brain function biomarkers for post-stroke cognitive impairment
Comparison of differences in brain activation \[HbO2 (mmol/L\*mm)\] between patients with post-stroke cognitive impairment and patients without post-stroke cognitive impairment or healthy subjects
Time frame: 1 day
Plan to share: Undecided
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