An interventional study of Tools for Life and Tools for Life + MISN in Alaska Native Youth Aged 14 - 24, Suicide, Attempted and Suicidal Ideation, sponsored by RAND. Completed at 2 sites in United States. Open to participants aged 14 Years to 24 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-10-27.
Sponsored by RAND · Not applicable, Interventional, and Prevention
Among 149 studies in Suicide, Attempted with a site in United States — 53 open to participants now, 58 under way, 1 of them phase 3. Suicide, Attempted · United States.
Among the 149 studies in Suicide, Attempted with a site in United States, this one is the 31st largest by enrollment of the 140 interventional ones, is one of 17 that started in 2022, is one of 121 with no phase, and was the 93rd registered.
281 studies on the registry are indexed under Suicide, Attempted; 91 are open to participants now.
This study's enrollment of 302 is above the median of 129 across 224 interventional studies indexed under Suicide, Attempted.
Browse Suicide, Attempted studies →53 of the 149 studies in Suicide, Attempted with a site in United States are open now, in 1 country. Each count lists the studies.
Of the 68 Suicide, Attempted studies recruiting now, 34 (50%) set no upper age limit and 33 (49%) stop at 75 or younger; 29 take children under 18; 11 take healthy volunteers.
This study: 14 Years to 24 Years · all sexes · healthy volunteers too.
The full table on the hub →149 studies; the count open now beside each. This study's row is marked.
First in 1999; this study’s year is marked. 17 started in 2022.
Median enrollment 117 across the 140 interventional studies, 225 across the 7 observational. Of the 87 that completed or were terminated, 30 (34%) have results posted.
5 of 149 have an industry lead sponsor. The 10 most frequent:
RAND is the lead sponsor of 114 studies on the registry; 6 are open to participants now.
RAND has 1 study filed under Suicide, Attempted — fewer than ten, so there is no comparison to draw.
30 of the studies in Suicide, Attempted with a site in United States that are under way reach primary completion within a year, 1 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT04763343Phase 3Tatiana Falcone, MDKetamine Treatment of Youth Suicide Attempters | 2027-02-28 |
| NCT07170657University of Texas Southwestern Medical CenterTeen Recovery Through Inspiration, Support, and Empowerment | 2026-11 |
| NCT06460220Jennifer HughesSAFETY-Parent: Online Learning Module to Support Parents of Suicidal Youth | 2026-12 |
| NCT06285708Ohio State UniversityEnhancing the Effectiveness of Prolonged Exposure Among Suicidal Individuals With PTSD | 2026-12 |
| NCT04578938Rebecca PriceKetamine + Cognitive Training for Suicidality in the Medical Setting | 2026-12-02 |
Among the 149 studies in Suicide, Attempted with a site in United States, from their registry updates:
Two interventions will be delivered virtually to American Indian/Alaska Native youth who have been hospitalized with suicidal attempt, suicidal ideation, or associated risk behaviors, including alcohol-related injury.
The investigators will conduct a randomized controlled trial whereby Alaska Native (AN) youth who are hospitalized for suicide risk will be randomly assigned to either Qungasvik/Tools for Life or Tools for Life + Motivational Interviewing Social Network (MISN) intervention after their baseline survey, and followed up at 3-, 6-, and 12 months. All youth will receive Tools for Life and two 30-minute virtual follow-up visits (at 2- and 6-weeks post intervention) focused on connectivity to culture and obtaining support from intergenerational social networks in their home communities. Half of the youth will also receive MISN in addition to Tools for Life. Both interventions will be delivered virtually by a wellness team comprised of Alaska Native community behavioral health aides, prevention specialists and/or Elders who function in their communities as natural healers.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
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All youth will receive the Tools for Life (Qungasvik) intervention. Tools for Life is an evidence-based, community-developed intervention focused on providing protective cultural experiences for Alaska Native youth to address suicide risk and alcohol use.
Behavioral: Tools for Life
Half of the youth will will also receive MISN in addition to the Tools for Life intervention. MISN is an evidence-based treatment that augments motivational interviewing with personal social network composition and structure visualization as a means to cultivating healthy social networks and cultural worlds.
Behavioral: Tools for Life + MISN
Tools for Life focuses on empowering youth to learn more about their culture and their identity.
Tools for Life focuses on empowering youth to learn more about their culture and their identity. MISN focuses on helping youth get support from their community and social networks.
Suicide intent/risk
We will use the Suicidal Ideation Attributes Scale (SIDAS) \[0 = Never, 10 = Always\]
Time frame: Change from baseline to 3 months
Suicide intent/risk
We will use the Suicidal Ideation Attributes Scale (SIDAS) \[0 = Never, 10 = Always\]
Time frame: Change from baseline to 6 months
Suicide intent/risk
We will use the Suicidal Ideation Attributes Scale (SIDAS) \[0 = Never, 10 = Always\]
Time frame: Change from baseline to 12 months
Depression
Patient Health Questionnaire (PHQ-9) \[0 -not at all to 3-nearly every day\]
Time frame: Change from baseline to 3 months
Depression
Patient Health Questionnaire (PHQ-9) \[0 -not at all to 3-nearly every day\]
Time frame: Change from baseline to 6 months
Depression
Patient Health Questionnaire (PHQ-9) \[0 -not at all to 3-nearly every day\]
Time frame: Change from baseline to 12 months
Anxiety
Generalized Anxiety Disorder scale (GAD-7) \[0 -not at all to 3-nearly every day\]
Time frame: Change from baseline to 3 months
Anxiety
Generalized Anxiety Disorder scale (GAD-7) \[0 -not at all to 3-nearly every day\]
Time frame: Change from baseline to 6 months
Anxiety
Generalized Anxiety Disorder scale (GAD-7) \[0 -not at all to 3-nearly every day\]
Time frame: Change from baseline to 12 months
Frequency of alcohol use
Number of days used in the past 30 days. \[ 0 to 30\]
Time frame: Change from baseline to 3 months
Frequency of alcohol use
Number of days used in the past 30 days \[ 0 to 30\]
Time frame: Change from baseline to 6 months
Frequency of alcohol use
Number of days used in the past 30 days \[ 0 to 30\]
Time frame: Change from baseline to 12 months
Alcohol use consequences
Number of times in the past 3 months youth experience 4 different alcohol consequences \[0 = Never to 6 = 20 or more times\]
Time frame: Change from baseline to 3 months
Alcohol use consequences
Number of times in the past 3 months youth experience 4 different alcohol consequences \[0 = Never to 6 = 20 or more times\]
Time frame: Change from baseline to 6 months
Alcohol use consequences
Number of times in the past 3 months youth experience 4 different alcohol consequences \[0 = Never to 6 = 20 or more times\]
Time frame: Change from baseline to 12 months
Sobriety self-efficacy
Three items ask how sure youth are about staying sober from alcohol from 1= def drink to 5 = def not drink
Time frame: Change from baseline to 3 months
Sobriety self-efficacy
Three items ask how sure youth are about staying sober from alcohol from 1= def drink to 5 = def not drink
Time frame: Change from baseline to 6 months
Sobriety self-efficacy
Three items ask how sure youth are about staying sober from alcohol from 1= def drink to 5 = def not drink
Time frame: Change from baseline to 12 months
Intentions to be sober from alcohol
Youth report on intentions to be sober in the next 6 months from 1 = def yes to 4 = def no
Time frame: Change from baseline to 3 months
Intentions to be sober from alcohol
Youth report on intentions to be sober in the next 6 months from 1 = def yes to 4 = def no
Time frame: Change from baseline to 6 months
Intentions to be sober from alcohol
Youth report on intentions to be sober in the next 6 months from 1 = def yes to 4 = def no
Time frame: Change from baseline to 12 months
Social network composition
Participants will be asked to name 15 contacts ("alters") who are at least 18 years of age. Participants will rate each of the 15 people on the same set of questions with categorical response options (about demographics, relationship quality, likelihood to use drugs, etc.). For each participant, the selected responses will be summed across all of the network alters and divided by 15 to produce network composition percentages of the whole set of alters named by the participant (% of AI/ANs, % who engage in heavy drinking).
Time frame: Change from baseline to 3 months
Social network composition
Participants will be asked to name 15 contacts ("alters") who are at least 18 years of age. Participants will rate each of the 15 people on the same set of questions with categorical response options (about demographics, relationship quality, likelihood to use drugs, etc.). For each participant, the selected responses will be summed across all of the network alters and divided by 15 to produce network composition percentages of the whole set of alters named by the participant (% of AI/ANs, % who engage in heavy drinking).
Time frame: Change from baseline to 6 months
Social network composition
Participants will be asked to name 15 contacts ("alters") who are at least 18 years of age. Participants will rate each of the 15 people on the same set of questions with categorical response options (about demographics, relationship quality, likelihood to use drugs, etc.). For each participant, the selected responses will be summed across all of the network alters and divided by 15 to produce network composition percentages of the whole set of alters named by the participant (% of AI/ANs, % who engage in heavy drinking).
Time frame: Change from baseline to 12 months
Social network structure
Participants will rate the relationship strength between each of the 15 named alters. For each alter pair participants will rate if the two people know each other and, if yes, have individuals connected recently. Measures of network structure (i.e., network "connectedness") will be constructed from the set of evaluations for each participant. For example, network "density" will be constructed for the network overall, which is calculated by summing the number of alter pairs who know each other and dividing by the total number of possible ties among 15 alters (105). Individual alter "centrality" will be calculated by summing the number of connections each individual alter has with other alters in the network.
Time frame: Change from baseline to 3 months
Social network structure
Participants will rate the relationship strength between each of the 15 named alters. For each alter pair participants will rate if the two people know each other and, if yes, have individuals connected recently. Measures of network structure (i.e., network "connectedness") will be constructed from the set of evaluations for each participant. For example, network "density" will be constructed for the network overall, which is calculated by summing the number of alter pairs who know each other and dividing by the total number of possible ties among 15 alters (105). Individual alter "centrality" will be calculated by summing the number of connections each individual alter has with other alters in the network.
Time frame: Change from baseline to 6 months
Social network structure
Participants will rate the relationship strength between each of the 15 named alters. For each alter pair participants will rate if the two people know each other and, if yes, have individuals connected recently. Measures of network structure (i.e., network "connectedness") will be constructed from the set of evaluations for each participant. For example, network "density" will be constructed for the network overall, which is calculated by summing the number of alter pairs who know each other and dividing by the total number of possible ties among 15 alters (105). Individual alter "centrality" will be calculated by summing the number of connections each individual alter has with other alters in the network.
Time frame: Change from baseline to 12 months
Time spent around peers who use alcohol
Participants will report on how much time is spent around peers who drink from 0 = never to 3 = often
Time frame: Change from baseline to 3 months
Time spent around peers who use alcohol
Participants will report on how much time is spent around peers who drink from 0 = never to 3 = often
Time frame: Change from baseline to 6 months
Time spent around peers who use alcohol
Participants will report on how much time is spent around peers who drink from 0 = never to 3 = often
Time frame: Change from baseline to 12 months
Awareness of connectedness
Youth report on feelings of connectedness to community, family and environment from 1 = strongly agree to 5 strongly disagree
Time frame: Change from baseline to 3 months
Awareness of connectedness
Youth report on feelings of connectedness to community, family and environment from 1 = strongly agree to 5 strongly disagree
Time frame: Change from baseline to 6 months
Awareness of connectedness
Youth report on feelings of connectedness to community, family and environment from 1 = strongly agree to 5 strongly disagree
Time frame: Change from baseline to 12 months
Community protective factors
Youth Community Protective Factors Scale. Youth report on feelings about different protective factors from 1 = strongly agree to 5 strongly disagree
Time frame: Change from baseline to 3 months
Community protective factors
Youth Community Protective Factors Scale Youth report on feelings about different community protective factors from 1 = strongly agree to 5 strongly disagree
Time frame: Change from baseline to 6 months
Community protective factors
Youth Community Protective Factors Scale Youth report on feelings about different community protective factors from 1 = strongly agree to 5 strongly disagree
Time frame: Change from baseline to 12 months
Individual protective factors
Youth report on feelings about different individual protective factors from 1 = strongly agree to 5 strongly disagree
Time frame: Change from baseline to 3 months
Individual protective factors
Youth report on feelings about different individual protective factors from 1 = strongly agree to 5 strongly disagree
Time frame: Change from baseline to 6 months
Individual protective factors
Youth report on feelings about different individual protective factors from 1 = strongly agree to 5 strongly disagree
Time frame: Change from baseline to 12 months
Reasons for life
Brief Reasons for Life Scale from 1 not at all important to 5 very important
Time frame: Change from baseline to 3 months
Reasons for life
Brief Reasons for Life Scale from 1 not at all important to 5 very important
Time frame: Change from baseline to 6 months
Reasons for life
Brief Reasons for Life Scale from 1 not at all important to 5 very important
Time frame: Change from baseline to 12 months
Reflective processes
The Reflective Processes scale taps a culturally patterned type of awareness and youth report from from 1 = strongly agree to 5 strongly disagree
Time frame: Change from baseline to 3 months
Reflective processes
The Reflective Processes scale taps a culturally patterned type of awareness and youth report from from 1 = strongly agree to 5 strongly disagree
Time frame: Change from baseline to 6 months
Reflective processes
The Reflective Processes scale taps a culturally patterned type of awareness and youth report from from 1 = strongly agree to 5 strongly disagree
Time frame: Change from baseline to 12 months
PDFs hosted by the registry, ClinicalTrials.gov.
Plan to share: No — The investigators will share only deidentified, aggregate data.
Ran from Dec 2022 to primary completion in Jan 2026, 37 months.
Of 145 non-industry interventional studies with no phase under Suicide, Attempted, half reached primary completion within 37 months of starting (the median), counting those still running; a quarter within 21 and three quarters within 56. This study's 37 months is close to that.
Counting every sponsor, half of 147 studies reached it within 37 months; a quarter within 20 and three quarters within 56.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is completed, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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