An interventional study of With robot assistance and traditional rehabilitation in Knee Injuries and Disorders, sponsored by Peking University Third Hospital. Recruiting at 1 site in China. Open to participants aged 20 Years to 60 Years. Per ClinicalTrials.gov, last updated 2026-09-15.
Sponsored by Peking University Third Hospital · Not applicable, Interventional, and Other
The goal of this clinical trial is to assess the effectiveness of isokinetic rehabilitation training under optimal stiffness in patients undergoing knee joint rehabilitation. The main questions it aims to answer are:
Participants will:
267 studies on the registry are indexed under Knee Injuries; 59 are open to participants now.
This study's planned enrollment of 12 is below the median of 49 across 178 interventional studies indexed under Knee Injuries.
Browse Knee Injuries studies →Peking University Third Hospital is the lead sponsor of 752 studies on the registry; 273 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
4. Postoperative period of 3-6 months. 5. No restriction in knee extension or flexion movements.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
The human immunodeficiency virus, which weakens the immune system.
Many studies now accept people whose HIV is controlled on treatment, judged by the viral load and the CD4 count. Check the limits this study sets.
Hepatitis B is a virus that infects the liver. These are separate tests: HBsAg positive usually means a current infection (a recent vaccination can briefly cause it too); total anti-HBc (HBcAb) positive means an infection now or in the past; HBV DNA measures how much virus is in the blood.
Some studies accept a past infection if HBV DNA is undetectable, sometimes with antiviral medicine during the study. Check what this study allows.
The New York Heart Association’s four classes of how much heart failure limits physical activity.
Studies set their own limit — many outside heart failure leave out class III–IV, while heart failure studies may ask for a particular class. Check the class this study names.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
HIV
The human immunodeficiency virus, which weakens the immune system.
Many studies now accept people whose HIV is controlled on treatment, judged by the viral load and the CD4 count. Check the limits this study sets.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Hepatitis B tests
Hepatitis B is a virus that infects the liver. These are separate tests: HBsAg positive usually means a current infection (a recent vaccination can briefly cause it too); total anti-HBc (HBcAb) positive means an infection now or in the past; HBV DNA measures how much virus is in the blood.
Some studies accept a past infection if HBV DNA is undetectable, sometimes with antiviral medicine during the study. Check what this study allows.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
NYHA class (heart failure)
The New York Heart Association’s four classes of how much heart failure limits physical activity.
Studies set their own limit — many outside heart failure leave out class III–IV, while heart failure studies may ask for a particular class. Check the class this study names.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
In this clinical trial, 6 patients who meet the inclusion criteria will be enrolled in the experimental group to undergo rehabilitation using a portable isokinetic device.
Device: With robot assistance
The control group will consist of 6 patients who meet the inclusion criteria and will undergo traditional isotonic and isometric rehabilitation
Behavioral: traditional rehabilitation
Use a portable isokinetic device
Use traditional isotonic and isometric rehabilitation
Cross-sectional area of the quadriceps
Using MRI，Up to 6 weeks
Time frame: Before 1st practice, and after 12th practice (6 weeks * 2 practices/week = 12 practices)
Cross-sectional area of the hamstrings
using MRI， Up to 6 weeks
Time frame: Before 1st practice, and after 12th practice (6 weeks * 2 practices/week = 12 practices)
Peak flexion and extension knee torque
Using an integrated torque sensor
Time frame: During each practice (6 weeks * 2 practices/week = 12 practices).
Average flexion and extension knee torque
Time frame: During each practice (6 weeks * 2 practices/week = 12 practices).
Flexion and extension knee work
Work=Torque\*Speed
Time frame: In each ptractice (6 weeks * 2 practices /week = 12 practices).
Thigh circumference
10 cm proximal to the superior pole of the patella
Time frame: In each ptractice (6 weeks * 2 practices /week = 12 practices).
Knee joint pain score (VAS score)
Up to 6 weeks，max. =100, min. =0, Visual Analogue Scale=VSA, A higher score indicates greater pain intensity.
Time frame: Before 1st practice, and after 12th practice (6 weeks * 2 practices/week = 12 practices)
Surface electromyography signals of quadricep and hamstrings
SEMG signals are used to evaluate the instant effect brought by the optimal stiffness.
Time frame: During optimal stiffness measurements
PDFs hosted by the registry, ClinicalTrials.gov.
Plan to share: Undecided
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