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CompletedNCT06637319Updated Jan 28, 2026

Prevalence of Major Vessels Underlying the Potential Incision Site for Emergency Front of Neck Airway Access in Adult Surgical Patients With Impalpable Neck Anatomy

An observational study in Airway Complication of Anesthesia, sponsored by Mount Sinai Hospital, Canada. Completed at 1 site in Canada. Open to participants aged 18 Years to 80 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-01-28.

Sponsored by Mount Sinai Hospital, Canada · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
50
Ages
18 Years to 80 Years
Sex
All
01

Study summary

Patients undergoing general anesthesia require assistance with their breathing and with the delivery of oxygen to their lungs. To achieve this, an anesthesiologist inserts a type of plastic breathing tube into the airway via the mouth called an endotracheal tube or laryngeal mask airway. In rare circumstances, the anesthesiologist may not be able to adequately provide oxygen via these methods. In this life-threatening situation, an anesthesiologist may be forced to make an incision in the front of the neck to access the trachea (windpipe) so that emergency oxygen can be provided. This life-saving technique is known as emergency front-of-neck access (eFONA) and is used to prevent low oxygen levels which cause irreversible brain damage and/or death.

This rarely performed procedure carries a risk of harm from bleeding, injury to the airway or inability to access the trachea to provide oxygen. Emergency front of neck access is more likely to be required in patients with abnormal airway anatomy, for example, in patients with obesity and large neck circumference, neck cancer, or a history of head and neck radiation therapy. Though the optimal technique for eFONA is not clear, prominent guidelines advise the use of an 8-10cm incision upwards from the top of the breastbone in order to identify airway structures which cannot be easily felt by the anesthesiologist from the front of the intact neck. This differs from patients who have airway structures which may be easily located at the front of the neck, whereby a smaller incision may be made or a needle inserted into the trachea (widepipe) to provide oxygen. The neck contains major blood vessels which lie close to the airway and these blood vessels may be injured during the 8-10cm incision, creating further difficulty accessing the airway to provide life-saving oxygen.

This study aims to assess for the presence and size of major blood vessels which may be damaged by this incision by using non-invasive ultrasound which will be placed on the skin of your neck to assess for such blood vessels prior to you undergoing anesthesia.

Our study aims to assess the normal anatomy in the adult population such as yourself to understand what to expect when managing patients who require this life-saving therapy.

02

Conditions studied

  • Airway Complication of Anesthesia

Keywords

  • font of neck access
  • blood vessels
  • ultrasound
03

In context

Lead sponsor

Mount Sinai Hospital, Canada is the lead sponsor of 157 studies on the registry; 33 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Healthy Volunteers

Inclusion criteria

  • Healthy volunteers
  • Ability to understand the rationale of the study assessments and to provide signed consent
  • Ability to safely and comfortably take part in the study protocol

Exclusion criteria

Exclusion Criteria:

  • Participant refusal
  • Participant less than 18 years old or older than 80 years old
  • Participants who do not speak English or cannot give informed written consent without assistance
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
50 participants (actual)
Patient registry
No

Groups and cohorts

  • Healthy Volunteers

    Healthy volunteers \> 18 years of age

    Device: Ultrasound

Interventions

  • DeviceUltrasound

    Ultrasound scan of blood vessels where front of neck access vertical incision would take place in a cant intubate cant oxygenate scenario

06

What researchers measure

Primary outcomes

  1. Prevalence of blood vessels

    The prevalence of blood vessels at front of neck on ultrasound where an emergency front of neck access vertical incision would take place. In total five regions looked at: sternal notch, thyroid gland, cricoid cartilage, cricothyroid membrane and thyroid cartilage

    Time frame: During the procedure (30 minutes

Secondary outcomes

  1. Depth of blood vessels

    The height from skin to each blood vessels found on ultrasound

    Time frame: During the procedure (10 minutes)

  2. Diameter of blood vessels

    The widest measured diameter of each blood vessels on ultrasound

    Time frame: During the procedure (10 minutes)

  3. Distance from midline

    The distance of each blood vessel from midline on ultrasound

    Time frame: During procedure (10 minutes)

07

Study locations

1 site
  • Mount Sinai Hospital
    Toronto, Ontario M5G1X5, Canada
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 28, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06637319
Lead sponsor
Mount Sinai Hospital, Canada
Responsible party
Sponsor
First posted
Oct 15, 2024
Start date
Dec 1, 2024
Primary completion
Feb 15, 2025
Completion
Jun 30, 2025
Last update
Jan 28, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Sep 2024. You cannot join it, but the record below documents what was studied.

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