An observational study in Hand Infections, Including Whitlows and Tendinous Infections, sponsored by Hospices Civils de Lyon. Active, not recruiting at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2024-10-08.
Sponsored by Hospices Civils de Lyon · Observational
Primary or secondary (post-traumatic infections, notably related to bites, wounds, etc.) infections of the hand are very common situations, even if the epidemiology is poorly understood. For example, hand bite injuries represent 1.2 million referrals to the healthcare system per year in the United States. Their nosological framework extends from simple infections of the skin and soft tissues such as whitlows, to potentially severe deep damage such as arthritis and osteitis, or phlegmons of the tendon sheaths. The diagnostic approach is not consensual, and the contribution of additional biological parameters (inflammatory syndrome) and morphological investigations (x-rays, ultrasound, CT-scan or MRI) is not codified. Microbiology seems dominated by Staphylococcus aureus, but few studies have precisely described the microbial etiology. Consequently, probabilistic antibiotic therapy and the need to take bacteriological samples for secondary adaptation are not standardized. Likewise, surgical strategies (abstention, systematic washing or depending on evolution) remain operator dependent. We consequently aim to described diagnostic, management and related outcomes or hand infections in a specialized tertiary care center.
6,687 studies on the registry are indexed under Infections; 807 are open to participants now.
This study's planned enrollment of 1,400 is above the median of 240 across 2,136 observational studies indexed under Infections.
Browse Infections studies →Hospices Civils de Lyon is the lead sponsor of 1,826 studies on the registry; 439 are open to participants now.
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Patients will be selected from the data base of the hand emergency surgery department of our tertiary care center, based on a principal or secondary diagnosis of BJI appearing alone or in combination with either sepsis or a specific surgical procedure - 1400 potential patients.
Exclusion Criteria:
Description of whitlows, tendinous infections and septic arthritis diagnostic, management and outcome Descriptive study, no intervention
Other: Failure rates
Describe the management failure rate for hand infections, including panariasis, phlegmons and arthritis.
Percentage of treatment failure during the management of hand infections.
Treatment failure will be defined as infection persistence or relapse, need of unplanned surgery for septic reason or infection-related death.
Time frame: between 01/01/2014 and 31/12/2023.
This study is active, not recruiting, as verified in Oct 2024. You cannot join it, but the record below documents what was studied.
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Hospices Civils de Lyon