An observational study in Osteoarticular Infection, Intensive Care Patients and Prosthetic Joint Infection, sponsored by Assistance Publique - Hôpitaux de Paris. Suspended at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-06-02.
Sponsored by Assistance Publique - Hôpitaux de Paris · Observational
This is an ambispective observational study of patients admitted to intensive care with a diagnosis of joint prosthesis infection (mainly knee and hip prostheses). The main objective of the study is to describe the profile, care trajectories during the stay (before or after surgery) and prognosis of patients admitted to critical care with such an infection. We also aim to compare prognosis between different groups of patients sharing the same profile and care trajectory, and to assess independent risk factors associated with 2-year mortality among the study population. Finally, we will describe the microbiological and resistance profile of severe osteoarticular device infections requiring critical care admission in France.
This is a descriptive and analytical observational study open to all French public and private hospitals.
Patient data will be retrieved prospectively from patient source files. Only 2-year data (vital status, functional data) will be collected specifically for the study, by telephone contact with the patient or his or her support person.
1,899 studies on the registry are indexed under Sepsis; 462 are open to participants now.
This study's planned enrollment of 150 is close to the median of 160 across 931 observational studies indexed under Sepsis.
Browse Sepsis studies →Assistance Publique - Hôpitaux de Paris is the lead sponsor of 3,505 studies on the registry; 1,006 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Critical care patients (intensive care and continuing care), admitted between 2018 and 2022 with a principal or associated diagnosis of prosthetic joint infection.
Exclusion Criteria:
All patients admitted to intensive care during the study period
The profile, trajectories of care during the stay (before or after surgery) and the prognosis of patients admitted to intensive care for joint prosthesis infection over a 2-year period after admission to intensive care.
Time frame: 2 years
Composite endpoint reflecting poor clinical outcome
* Mortality, measured in critical care, at 30 days, 1 year and 2 years * Therapeutic failure at 2 years, defined as mechanical or septic failure. * Functional failure at 2 years, defined as failure to resume walking and usual activities, to return home, or to regain autonomy.
Time frame: 2 years
Mortality at 2 years
Time frame: 2 years
Description of pathogens found in intraoperative samples, and their resistance spectrum
Time frame: 2 years
Plan to share: No
No publications or documents are linked to this record.
This study is suspended, as verified in May 2026. You cannot join it, but the record below documents what was studied.
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Assistance Publique - Hôpitaux de Paris