An interventional study of otago excercises and Medical ADT treatment in Prostate, sponsored by MTI University. Completed at 1 site in Egypt. Open to male participants aged 50 Years to 75 Years. Per ClinicalTrials.gov, last updated 2025-04-02.
Sponsored by MTI University · Not applicable, Interventional, and Treatment
Androgen deprivation therapy (ADT) is a common treatment for older men with advanced prostate cancer (PCa) but is associated with numerous deleterious health effects that may accentuate age associated physiological declines.
Decreased lower body muscle mass and strength, cognitive decline, worsen fatigue and progressive loss of BMD following initiating ADT could put prostate cancer survivors at higher risk of impaired physical functioning performance and subsequently developing falls. Otago training is helpful, and one of the most powerful interventions where the original randomized controlled trials reported improvements in functional outcomes and a 35% reduction in falls for frail, high-risk older adults (Shubert et al., 2018). In Egypt, there are little researches about Otago Exercise Program.
Androgen deprivation therapy (ADT) is a common treatment for older men with advanced prostate cancer (PCa) but is associated with numerous deleterious health effects that may accentuate age associated physiological declines.
Decreased lower body muscle mass and strength, cognitive decline, worsen fatigue and progressive loss of BMD following initiating ADT could put prostate cancer survivors at higher risk of impaired physical functioning performance and subsequently developing falls.
Otago training is helpful, and one of the most powerful interventions where the original randomized controlled trials reported improvements in functional outcomes and a 35% reduction in falls for frail, high-risk older adults (Shubert et al., 2018). In Egypt, there are little researches about Otago Exercise Program.
Exercise is well-known as an economic and key adjuvant treatment in clinical oncology that improves QOL of cancer survivors. Many studies focused on investigating the benefits of exercise interventions on preventing falls and improving physical performance of older adults. Combination of strength and functional balance exercise has been demonstrated as an effective method to improve balance performance, rather than strength training alone
6,370 studies on the registry are indexed under Prostatic Neoplasms; 1,397 are open to participants now.
This study's enrollment of 110 is above the median of 58 across 4,821 interventional studies indexed under Prostatic Neoplasms.
Browse Prostatic Neoplasms studies →MTI University is the lead sponsor of 58 studies on the registry; 11 are open to participants now.
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Men aged 50 years or older diagnosed with adenocarcinoma prostate cancer.
Exclusion Criteria:
This group included 52 patients receive Otago exercise training for 45 minutes after each session with routine medical care for prostatic cancer patients
Other: otago excercises
This group included 52 patients receive routine medical care for prostatic cancer patients.
Other: Medical ADT treatment
Otago training is helpful, and one of the most powerful interventions where the original randomized controlled trials reported improvements in functional outcomes and a 35% reduction in falls for frail, high-risk older adults (Shubert et al., 2018). In Egypt, there are little researches about Otago Exercise Program. Exercise is well-known as an economic and key adjuvant treatment in clinical oncology that improves QOL of cancer survivors. Many studies focused on investigating the benefits of exercise interventions on preventing falls and improving physical performance of older adults. Combination of strength and functional balance exercise has been demonstrated as an effective method to improve balance performance, rather than strength training alone
Medical ADT treatment according to patient age, prostatic cancer stage
Also known as: control
Isometric knee muscle strength
will be used to evaluate knee extension and flexion isometric strength.
Time frame: base line and 24 weeks
Bone mineral density (BMD
will be used to evaluate Bone mineral density of the lumbar spine (LS) and femoral neck (FN)
Time frame: base line and 24 weeks
Timed up and go (TUG) test
will be used to measure basic mobility skills. The measurement outcome for TUG is the time it takes to rise up out of a chair, walk 3 m away from the chair, walk 3 m back to the chair, and return to the seated position
Time frame: base line and 24weeks
Berg Balance Scale (BBS)
Used to assess the patient ability to balance his /her body during activities and risk of fall
Time frame: base line and 24weeks
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Mar 2025. You cannot join it, but the record below documents what was studied.
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