An interventional study of Creatine and Placebo in Improve Muscle Performance in Young Adults, sponsored by University of Regina. Recruiting at 1 site in Canada. Open to participants aged 18 Years to 39 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-09-20.
Sponsored by University of Regina · Not applicable, Interventional, and Treatment
The purpose is to compare the effects of bolus ingestion (5 grams) vs. intermittent ingestion (2 x 2.5 grams) of creatine supplementation vs. placebo for 21 days on measures of body composition (lean tissue mass-indicator of muscle mass, total body water) and muscle performance (i.e., power, strength, endurance).
Creatine is a naturally occurring compound produced in the liver and brain. Creatine can also be found in food products such as red meat and seafood or through commercially available manufactured creatine products (i.e. creatine supplementation).
Evidence-based research shows that creatine supplementation improves measures of body composition and muscle performance. However, the optimal creatine supplementation protocol to achieve these benefits is unknown.
University of Regina is the lead sponsor of 56 studies on the registry; 22 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
(Serving 1: 5 grams of creatine monohydrate + 3 grams of placebo in the morning; Serving 2: 8 grams of placebo in the evening) for 21 days.
Dietary Supplement: Creatine
(Serving 1: 2.5 grams of creatine monohydrate + 5.5 grams of placebo in the morning; Serving 2: 2.5 grams of creatine monohydrate + 5.5 grams of placebo in the evening) for 21 days.
Dietary Supplement: Creatine
(Servings 1: 8 grams of placebo in the morning; Serving 2: 8 grams of placebo in the evening) for 21 days.
Dietary Supplement: Placebo
Creatine monohydrate
Maltodextrin
Whole-body lean mass (kg)
Bioelectrical impedance analysis
Time frame: baseline, day 21
Strength
1-repetition maximum leg press and chest press (kg)
Time frame: baseline, day 21
Endurance
Repetitions to fatigue for leg press and chest press (total number)
Time frame: baseline, day 21
Hydration
Total body water (kg) using bioelectrical impedance analysis
Time frame: baseline, day 21
Power
Vertical Jump (cm)
Time frame: baseline, day 21
Power
Medicine Ball Throw (feet)
Time frame: baseline, day 21
Plan to share: No
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University of Regina