An observational study in End-stage Renal Disease, sponsored by Yuanjun Yang. Not yet recruiting. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2024-09-19.
Sponsored by Yuanjun Yang · Observational
Residual renal function (RRF) characteristically declines after patients with end-stage renal disease (ESRD) initiate dialysis. Although RRF preservation correlates with improved patient\'s quality of life and survival prospects, poor understanding of the pathophysiology underlying RRF decline limits protection strategies.
Hemodialysis (HD) is the primary renal replacement therapy for patients with end-stage renal disease. However, residual renal function (RRF) characteristically declines after these individuals start dialysis. This loss of RRF not only impacts the adequacy of dialysis and control of complications but also affects the patient\'s quality of life and survival prospects. Due to a lack of clear understanding regarding the pathophysiology underlying this decline in RRF, no effective strategies exist for its preservation at present. The objective of this study is to explore the changes in renal perfusion during hemodialysis in patients with end-stage renal disease, and provide a new idea for protection of RRF. This study was an observational study, and no interventions were performed.
3,840 studies on the registry are indexed under Kidney Diseases; 500 are open to participants now.
This study's planned enrollment of 20 is below the median of 192 across 1,033 observational studies indexed under Kidney Diseases.
Browse Kidney Diseases studies →Yuanjun Yang is the lead sponsor of 6 studies on the registry; 4 are open to participants now.
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First Medical Center of Chinese PLA General Hospital
Exclusion Criteria:
renal perfusion
Changes in renal perfusion during hemodialysis in patients with end-stage renal disease
Time frame: one day
diastolic blood pressure
diastolic blood pressure during hemodialysis in patients with end-stage renal disease
Time frame: one day
systolic blood pressure
systolic blood pressure during hemodialysis in patients with end-stage renal disease
Time frame: one day
urine volume
Urine volume within 10 months of starting dialysis
Time frame: 10 months
No study locations are listed for this record.
This study is not yet recruiting, as verified in Sep 2024. You cannot join it, but the record below documents what was studied.
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Yuanjun Yang