An observational study in Bipolar Disorder, sponsored by Karolinska Institutet. Active, not recruiting at 1 site in Sweden. Open to participants aged 18 Years to 100 Years. Per ClinicalTrials.gov, last updated 2025-02-19.
Sponsored by Karolinska Institutet · Observational
Previous studies indicate an association between severe psychiatric disorders, such as bipolar disorder, and increased risk of venous thromboembolism. However, to which extent this association is influenced by lithium treatment is currently unknown. In this prospective cohort study, the investigators aim to investigate the effect of bipolar disorder and lithium treatment on coagulation and the counterpart fibrinolysis.
The investigators will analyse differences in coagulation
1,601 studies on the registry are indexed under Bipolar Disorder; 254 are open to participants now.
This study's enrollment of 68 is below the median of 160 across 329 observational studies indexed under Bipolar Disorder.
Browse Bipolar Disorder studies →Karolinska Institutet is the lead sponsor of 1,113 studies on the registry; 267 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients diagnosed with bipolar disorder but not yet treated with lithium, where there is a decision by the patient and the responsible doctor to start lithium treatment. Patients are recruited in specialized care.
Exclusion Criteria:
Extracellular vesicles
Counts of plasma extracellular vesicles originating from blood platelets, leukocytes and vascular endothelial cells.
Time frame: From enrollment to end of examination at 2 years
Hemostatic potential
Overall hemostatic potential (OHP), coagulation potential (OCP) fibrinolytic potential (OFP) i citrate plasma.
Time frame: From enrollment to end of examination at 2 years
Plasma proteins of coagulation- or fibrinolysis-related processes
Concentration in plasma of proteins involved in coagulation or fibrinolysis such as von Willebrand factor
Time frame: From enrollment to end of examination at 2 years
Plan to share: No — Not planning to share IPD
No publications or documents are linked to this record.
This study is active, not recruiting, as verified in Feb 2025. You cannot join it, but the record below documents what was studied.
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Karolinska Institutet