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RecruitingNCT06564779NEMUpdated Apr 30, 2026

Development, Standardisation and Standardisation Project for a New Memory Assessment

An observational study in Memory Disorders, sponsored by University Hospital, Tours. Recruiting at 1 site in France. Open to participants aged 50 Years and older. Per ClinicalTrials.gov, last updated 2026-04-30.

Sponsored by University Hospital, Tours · Observational

From the registry’s dates

  • Started Nov 2024; still recruiting 1 year 11 months later.
Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
150
Ages
50 Years and older
Sex
All
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Study summary

Episodic memory (EM) is a neuropsychological marker of Alzheimer's disease (AD) (Thomas-Anterion, 2006). Current tests for its assessment do not take into account the identity and emotional aspects of memory (Van der Linden et al., 2018). However, there are models that integrate links with identity, self-awareness and experience. Pause et al. (2013) propose criteria to create ecological tools, including consideration of the emotional valence of memories and the spatio-temporal context of acquisition. In line with these criteria, we have developed a new tool: the NEM (New evaluation of Episodic Memory). Preliminary studies show different response profiles on the NEM among patients (Launay et al., 2023). We now want to evaluate the relevance of this tool in the differential diagnosis of AD.

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Conditions studied

  • Memory Disorders

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Keywords

  • Alzheimer
  • Episodic memory
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In context

Memory Disorders

373 studies on the registry are indexed under Memory Disorders; 67 are open to participants now.

This study's planned enrollment of 150 is below the median of 187 across 62 observational studies indexed under Memory Disorders.

Browse Memory Disorders studies →

Lead sponsor

University Hospital, Tours is the lead sponsor of 307 studies on the registry; 79 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
50 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patient attending a memory consultation for suspected Alzheimer's disease.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Age ≥ 50 years
  • Ability to understand judged sufficient by the assessor;
  • Amnesic MCI profile (Petersen, 2003) during the 1st medical consultation prior to the assessment being prescribed.

Exclusion criteria

Exclusion Criteria:

  • Severe auditory and/or visual sensory impairment not compatible with neuropsychological assessment;
  • Judged fit to take the test by the assessor;
  • Patient under guardianship, curatorship or family guardianship;
  • Opposition to data processing.
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Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
150 participants (estimated)
Patient registry
No

Groups and cohorts

  • group intervention

    patients benefiting from the new memory assessment

    Other: New memory assessment

Interventions

  • OtherNew memory assessment

    The intervention is part of the neuropsychological assessment carried out as part of routine care. It consists of carrying out the neuropsychological tests traditionally used to investigate the diagnostic hypothesis of Alzheimer's disease.

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What researchers measure

Primary outcomes

  1. Score total NEM (new memory assessment)

    Sum of the episodic elements

    Time frame: baseline

Secondary outcomes

  1. NEM sub-scores

    Sum of the episodic elements by category

    Time frame: baseline

  2. Total RL/RI 16 Recall

    (Van der Linden et al., 2014)

    Time frame: baseline

  3. Delayed Mem Logic Recall

    (MEM IV, Wechsler, 2014)

    Time frame: baseline

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Study locations

1 of 1 sites recruiting
  • University hospital
    Tours, 37044, France
    Recruiting
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References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

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Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Started Nov 2024 (actual). Primary completion is estimated for Nov 2028, 48 months after the start.

Of 23 observational studies under Memory Disorders, half reached primary completion within 37 months of starting (the median), counting those still running; a quarter within 22 and three quarters within 208. This study's planned 48 months is above that.

How these figures are worked out, and which studies are left out of them.

Registered
Aug 19, 2024
First posted
Aug 21, 2024
StartActual
Nov 22, 2024
Primary completionEst.
Nov 2028
CompletionEst.
Nov 2028
Last update
Apr 30, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Apr 30, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT06564779
Responsible party
Sponsor
First posted
Aug 21, 2024
Start date
Nov 22, 2024
Primary completion
Nov 2028 (estimated)
Completion
Nov 2028 (estimated)
Last update
Apr 30, 2026

Study contacts

Alix LAUNAY
Contact
a.launay@chu-tours.fr
0247470458 ext. +33
Alix LAUNAY
principal investigator · Tours University Hospital

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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