An observational study in Liver Metastases, sponsored by Azienda Ospedaliero Universitaria Maggiore della Carita. Not yet recruiting. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2024-08-07.
Sponsored by Azienda Ospedaliero Universitaria Maggiore della Carita · Observational
Liver metastases (LM) are common in various types of malignant diseases, either at the diagnosis of the primary tumour or at a later time point. While the resection of colorectal LM (CRLM) is a well-established procedure, with survival rates superior to chemotherapy alone, controversial data still exist on liver resection for non-colorectal LM (NCRLM) (2, 3). These patients comprise a diverse and heterogeneous group usually excluded from surgery due to advanced tumour stage or the presence of concomitant extrahepatic disease. To date, no randomized clinical trial on the surgical treatment of NCRLM has been conducted, and only few retrospective reports are available.The scope of this research project is to develop a large registry of patients undergoing liver surgery for non-colorectal liver metastases.
3,517 studies on the registry are indexed under Neoplasm Metastasis; 885 are open to participants now.
This study's planned enrollment of 300 is above the median of 121 across 594 observational studies indexed under Neoplasm Metastasis.
Browse Neoplasm Metastasis studies →Azienda Ospedaliero Universitaria Maggiore della Carita is the lead sponsor of 54 studies on the registry; 20 are open to participants now.
Counted across the registry records on this site, refreshed daily.
All patients with a diagnosis, based on imaging methods and histologically confirmed, of NCRLM, consecutively referred to centres with expertise in hepatobiliary surgery will be evaluated for inclusion. For the diagnosis and staging of disease the participating centres will refer to the guidelines for NCRLM, together with the established clinical habits present in each centre
Exclusion criteria
Resection of non-colorectal liver metastases
Also known as: hepatectomy
Overall Survival
Overall Survival defined as the time elapsed between the date of resective surgery and the date of death for any reason. Patients who are surviving at the end of observation will be considered "censored" at the date of the last available follow-up.
Time frame: From date of enrollment until the date of death from any cause assessed up to 36 months
Disease-free Survival
Disease-free Survival defined as the time from resective surgery to the date of first relapse or last available follow-up, whichever occurs first
Time frame: From date of enrollement until the date of first documented progression assessed up to 36 months
No study locations are listed for this record.
Plan to share: No
No publications or documents are linked to this record.
This study is not yet recruiting, as verified in Aug 2024. You cannot join it, but the record below documents what was studied.
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Azienda Ospedaliero Universitaria Maggiore della Carita