An interventional study of High velocity low amplitude thoracic spine manipulation and Sham in Muscle Weakness, sponsored by University of New England. Completed at 1 site in United States. Open to participants aged 18 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-08-02.
Sponsored by University of New England · Not applicable, Interventional, and Treatment
The goal of this trial was to determine if a mid-thoracic high velocity low amplitude spinal manipulation improves force output in those with unilateral hip adductor weakness. The main aims were to determine if the intervention:
Improved hip adductor force and muscle activation immediately and 48 h post manipulation compared to a control group.
Improved gluteus maximus and latissimus dorsi force and muscle activation immediately and 48 h post manipulation compared to a control group.
Strength and muscle activation of the hip adductors, hip extensors (gluteus maximus), and shoulder extensors (latissimus dorsi) were measured prior to, immediate after, and 48 hours after receiving a high velocity low amplitude manipulation to the thoracic spine. The manipulation was performed by a licensed chiropractor.
A control group received a validated sham manipulation to the thoracic spine. Participants were blinded to group assignment.
477 studies on the registry are indexed under Muscle Weakness; 73 are open to participants now.
This study's enrollment of 40 is close to the median of 44 across 362 interventional studies indexed under Muscle Weakness.
Browse Muscle Weakness studies →University of New England is the lead sponsor of 12 studies on the registry; 1 is open to participants now.
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Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Any known active cancer/ Bone Cancer Osteoporosis or other metabolic bone disorders Signs of spinal cord compression Nerve root compression with increasing neurologic deficit Signs of Vertebrobasilar insufficiency/ cervical artery abnormalities Bleeding Diatheses Angina pectoris
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Cancer that has spread from where it began to other parts of the body. “Metastatic” cancer is cancer that has spread this way.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Metastases
Cancer that has spread from where it began to other parts of the body. “Metastatic” cancer is cancer that has spread this way.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Those in the intervention group received a high velocity low amplitude manipulation to the mid-thoracic spine provided by a licensed chiropractor.
Procedure: High velocity low amplitude thoracic spine manipulation
Those in the control group received a validated sham manipulation to the mid-thoracic spine. The sham manipulation was done so that there was minimal downward force applied to the spine.
Procedure: Sham
Participants were supine on a treatment table. The chiropractor determined levels of apparent spinal dysfunction by means of static palpation. Participants were then asked to curl forward and bring their knees to their chest as the chiropractor placed a fist just inferior to the targeted level, anywhere between the T4 - T10 vertebrae. The participant was instructed to inhale and then exhale, at which point the chiropractor lowered the participant's torso back to the table and delivered a thrust using his body into his fist.
A previously validated physiologically inert manual procedure to the thoracic spine
Hip adductor force (weak limb)
Isometric force produced by the hip adductors in the weaker limb. Measured with a force transducer and reported in Newtons.
Time frame: Pre intervention, immediatly post intervention, 48 hours post intervention
Hip adductor muscle activity (weak limb)
Mean muscle activity during isometric contraction. Measured with surface electrode and reported as a percentage of maximum activation.
Time frame: Pre intervention, immediatly post intervention
Hip extension force (strong limb)
Isometric force produced by the hip extensors in the strong limb. Measured with a force transducer and reported in Newtons.
Time frame: Pre intervention, immediatly post intervention, 48 hours post intervention
Gluteus maximus muscle activity (strong limb)
Mean muscle activity during isometric contraction. Measured with surface electrode and reported as a percentage of maximum activation.
Time frame: Pre intervention, immediatly post intervention
Hip extension force (weak limb)
Isometric force produced by the hip extensors in the weak limb. Measured with a force transducer and reported in Newtons.
Time frame: Pre intervention, immediatly post intervention, 48 hours post intervention
Gluteus maximus muscle activity (weak limb)
Mean muscle activity during isometric contraction. Measured with surface electrode and reported as a percentage of maximum activation.
Time frame: Pre intervention, immediatly post intervention
Shoulder extension force (weak limb)
Isometric force produced by the shoulder extensors in the weak limb. Measured with a force transducer and reported in Newtons.
Time frame: Pre intervention, immediatly post intervention, 48 hours post intervention
Latissimus dorsi muscle activity (weak limb)
Mean muscle activity during isometric contraction. Measured with surface electrode and reported as a percentage of maximum activation.
Time frame: Pre intervention, immediatly post intervention
Shoulder extension force (strong limb)
Isometric force produced by the shoulder extensors in the strong limb. Measured with a force transducer and reported in Newtons.
Time frame: Pre intervention, immediatly post intervention, 48 hours post intervention
Latissimus dorsi muscle activity (strong limb)
Mean muscle activity during isometric contraction. Measured with surface electrode and reported as a percentage of maximum activation.
Time frame: Pre intervention, immediatly post intervention
Hip adductor muscle activity (strong limb)
Mean muscle activity during isometric contraction. Measured with a force transducer and reported in Newtons.
Time frame: Pre intervention, immediatly post intervention
Hip adductor force (strong limb)
Isometric force produced by the hip adductors in the strong limb. Measured with a force transducer and reported in Newtons.
Time frame: Pre intervention, immediatly post intervention, 48 hours post intervention
This study is completed, as verified in Jul 2024. You cannot join it, but the record below documents what was studied.
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University of New England