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CompletedNCT06527976Updated Jul 30, 2024

Dexamethasone Versus Demedetomidine Addition for Adductor Canal Block

An interventional study of Dexmedetomidine and Dexamethasone in Postoperative Pain, sponsored by Assiut University. Completed at 1 site in Egypt. Open to participants aged 20 Years to 60 Years. Per ClinicalTrials.gov, last updated 2024-07-30.

Sponsored by Assiut University · Not applicable, Interventional, and Prevention

From the registry’s dates

  • Registered 2 years 5 months after the study started (first participant enrolled Feb 2022, registered Jul 2024).
Phase
Not applicable
Study type
Interventional
Enrollment
90
Allocation
Randomized
Ages
20 Years to 60 Years
Sex
All
01

Study summary

Single-injection peripheral nerve block (PNB) is commonly used for perioperative analgesia and anesthesia. Three approaches for extending the duration of PNB include continuous PNB with catheter-based techniques, novel local anesthetics delivery systems and addition of novel adjuvants to local anesthetics.

02

Conditions studied

  • Postoperative Pain

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03

In context

Pain, Postoperative

5,093 studies on the registry are indexed under Pain, Postoperative; 1,140 are open to participants now.

This study's enrollment of 90 is above the median of 75 across 4,344 interventional studies indexed under Pain, Postoperative.

Browse Pain, Postoperative studies →

Lead sponsor

Assiut University is the lead sponsor of 4,901 studies on the registry; 2,098 are open to participants now.

Of its 13 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 60 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • elective operation
  • ASA STATUS I and II

Exclusion criteria

Exclusion Criteria:

  • patient refusal
  • ASA status III and IV
  • contraindications to local anesthesia
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Triple (Participant, Investigator, Outcomes assessor)
Enrollment
90 participants (actual)

Study arms

  • Active comparator
    dexmedetomidine

    Drug: Dexmedetomidine

  • Active comparator
    dexamethasone

    Drug: Dexamethasone

Interventions

  • DrugDexmedetomidine

    dexmedetomedine added to bupivacaine for adductor canal block

  • DrugDexamethasone

    dexamethasone added to bupivacaine for adductor canal block

06

What researchers measure

Primary outcomes

  1. visual analogue scale score

    scale of 11 points. zero=no pain, 10 = worest pain ever

    Time frame: 24 hours postoperative

Secondary outcomes

  1. analgesia duration

    pain free duration after block

    Time frame: 24 hours postoperative

  2. opioid consumption

    amount of opioid consumed postoperative

    Time frame: 24 hours postoperative

07

Study locations

1 site
  • Assiut university
    Assiut, 71111, Egypt
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 30, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT06527976
Lead sponsor
Assiut University
Responsible party
Rasha Hamed (Asisstant professor of anesthesia, Assiut University) — Principal investigator
First posted
Jul 30, 2024
Start date
Feb 15, 2022
Primary completion
Jan 1, 2024
Completion
Jan 1, 2024
Last update
Jul 30, 2024

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jul 2024. You cannot join it, but the record below documents what was studied.

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