CClinicalTrials.gg
CompletedNCT06510569Updated Jul 19, 2024

3D Evaluation of Clear Aligners Versus Fixed Orthodontic Treatment of Lower Anterior Crowding

An interventional study of U lab aligners and oramco bracket in Pathological Resorption of External Root, sponsored by Haidy Fekry. Completed at 2 sites in Egypt. Open to female participants aged 18 Years to 25 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-07-19.

Sponsored by Haidy Fekry · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 2 years 2 months after the study started (first participant enrolled Apr 2022, registered Jun 2024).
Phase
Not applicable
Study type
Interventional
Enrollment
20
Allocation
Randomized
Ages
18 Years to 25 Years
Sex
Female
01

Study summary

Evaluate and compare clear aligners versus fixed orthodontic treatment of lower anterior crowding with the use of cone-beam computed tomography within maximum 6 months or until correction of lower anterior crowding whichever is nearest to occur.

Read the detailed description

Group (A): Patients will be treated with conventional fixed orthodontic treatment in lower anterior crowding.

Group (B): Patients will be treated with clear aligner therapy in lower anterior crowding.

02

Conditions studied

  • Pathological Resorption of External Root
03

In context

Lead sponsor

This is the only study on the registry with Haidy Fekry as lead sponsor.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 25 Years
Sexes eligible
Female
Accepts healthy volunteers
Yes

Inclusion criteria

Adult female patients . age 18-25 y . Patients with mild to moderate lower anterior crowding (1 mm - 6 mm ) . Healthy compliant and motivated patient . full dentition except wisdom teeth .

Exclusion criteria

Exclusion Criteria:

Previous orthodontic treatments. Any systemic disease Pregnant and lactating female. pocket depth more than 5 mm.

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Crossover assignment
Masking
None (open label)
Enrollment
20 participants (actual)

Study arms

  • Experimental
    Clear aligner therapy

    U lab aligners

    Device: U lab aligners

  • Experimental
    Fixed orthodontic treatment

    Oromo bracket

    Device: oramco bracket

Interventions

  • DeviceU lab aligners

    Aligner group change the aligner every 10 days

  • Deviceoramco bracket

    changing orthodontic wire every one month

06

What researchers measure

Primary outcomes

  1. Correction of lower anterior crowding

    according to little irregularity index

    Time frame: 6 months

Other outcomes

  1. Root resorption

    CBCT evaluation of root resorption

    Time frame: 6 month

07

Study locations

2 sites
  • Al Azhar Universty
    Cairo, 002, Egypt
  • Haidy Fekry
    Zagazig, 002, Egypt
08

References and documents

Publications

  • Fiori A, Minervini G, Nucci L, d'Apuzzo F, Perillo L, Grassia V. Predictability of crowding resolution in clear aligner treatment. Prog Orthod. 2022 Nov 28;23(1):43. doi: 10.1186/s40510-022-00438-z. PubMed 36437397 ↗

Study documents

  • Study protocol · Apr 1, 2022

Documents are hosted by the registry — open the source record to download them.

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 19, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06510569
Lead sponsor
Haidy Fekry
Responsible party
Haidy Fekry (dentist, Faculty of Dental Medicine for Girls) — Sponsor-investigator
First posted
Jul 19, 2024
Start date
Apr 15, 2022
Primary completion
Apr 10, 2024
Completion
Jun 1, 2024
Last update
Jul 19, 2024

Study contacts

samir A ibrahim, proffesor
principal investigator · Al azhar universty

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jul 2024. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion