An interventional study of flexible ureteroscopic lithotripsy and percutaneous nephrolithotomy in Kidney Stone, sponsored by The First Hospital of Jilin University. Terminated at 1 site in China. Open to participants aged 18 Years to 70 Years. Per ClinicalTrials.gov, last updated 2026-05-08.
Sponsored by The First Hospital of Jilin University · Not applicable, Interventional, and Treatment
Urolithiasis is a common disease in urology. With the continuous progress of science and technology, the treatment of kidney lithiasis has undergone revolutionary changes, and the previously commonly used open surgical lithotomy method has been gradually eliminated, and replaced with less traumatic treatment methods. Percutaneous nephroscopy can theoretically treat the vast majority of kidney stones, especially in the treatment of kidney stones > 2 cm, it is widely used. With the development of ureteroscopy technology, the adaptation of ureteroscopy for the treatment of kidney stones has been expanding, and people have gradually paid attention to it with less damage and higher safety. This study aims to evaluate whether the efficacy and safety of soft ureteral lithotomy in the treatment of 2-4cm kidney stones is equal to that of percutaneous nephrolithotomy through prospective randomized controlled clinical trials, so as to provide more choices for physicians and patients, and provide theoretical basis for the standardization of clinical practice and the rationality of treatment.
598 studies on the registry are indexed under Kidney Calculi; 163 are open to participants now.
This study's enrollment of 224 is above the median of 90 across 461 interventional studies indexed under Kidney Calculi.
Browse Kidney Calculi studies →The First Hospital of Jilin University is the lead sponsor of 181 studies on the registry; 93 are open to participants now.
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Exclusion Criteria:
Procedure: flexible ureteroscopic lithotripsy
Procedure: percutaneous nephrolithotomy
This group of patients underwent flexible ureteroscopic lithotripsy.
This group of patients underwent percutaneous nephrolithotomy.
Stone free-rate (SFR)
Stone-free status is defined as the absence of any residual stone fragments or the presence of clinically meaningless residual stone fragments in the kidney, defined as ≤4mm, asymptomatic, non-obstructive, and non-infectious stone particles.
Time frame: All patients underwent a 2mm plain CT scan 1 month after surgery to assess final SFR.
Time of operation
Time of operation：From transurethral surgery to indwelling fistula or catheter.
Time frame: From transurethral surgery to indwelling fistula or catheter, assessed up to 6 hours.
Length of stay
Length of stay: from leaving the operating room to discharge
Time frame: From leaving the operating room to discharge,assessed up to 1 month.
Postoperative complication
Postoperative complication：Any surgery-related adverse events that occurred during or less than one month after surgery
Time frame: Any surgery-related adverse events that occurred during or less than one month after surgery.
Hospitalization costs
Hospitalization costs: Total costs during hospitalization
Time frame: From admission to discharge,assessed up to 1 month.
Plan to share: Yes — There is a plan to make IPD and related data dictionaries available.
Supporting information: Study protocol, Sap, Icf, Csr, Analytic code
No publications or documents are linked to this record.
This study is terminated, as verified in May 2026. You cannot join it, but the record below documents what was studied.
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The First Hospital of Jilin University