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CompletedNCT06502899Updated Jul 16, 2024

CMR in Myocardial Infarction with Nonobstructive Coronary Arteries

An observational study in Cardiac Magnetic Resonance, Myocardial Infarction with Nonobstructive Coronary Arteries and Strain, sponsored by The Affiliated Hospital of Xuzhou Medical University. Completed at 1 site in China. Per ClinicalTrials.gov, last updated 2024-07-16.

Sponsored by The Affiliated Hospital of Xuzhou Medical University · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
387
Sex
All
01

Study summary

MINOCA is accompanied by a worse prognosis, which is related to the inability to clarify the etiology.CMR has been explicitly recommended by guidelines as an etiologic diagnostic tool for MINOCA. Although CMR-related parameters, such as strain and ECV, have been shown to be associated with prognosis in patients with myocardial infarction. However, the relationship between CMR-strain or ECV and MINOCA is unclear. The aim of this study was to investigate the characterization of CMR-strain or ECV in patients with MINOCA and the relationship with prognosis.

02

Conditions studied

  • Cardiac Magnetic Resonance
  • Myocardial Infarction with Nonobstructive Coronary Arteries
  • Strain
  • Extracellular Volume
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In context

MINOCA

29 studies on the registry are indexed under MINOCA; 18 are open to participants now.

This study's enrollment of 387 is below the median of 500 across 20 observational studies indexed under MINOCA.

Browse MINOCA studies →

Lead sponsor

The Affiliated Hospital of Xuzhou Medical University is the lead sponsor of 70 studies on the registry; 33 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

We consecutively selected patients who were suspected of myocardial infarction with concomitant CAG from January 2019 to June 2024 at the Affiliated Hospital of Xuzhou Medical University. All patients completed CMR during hospitalization. hsTnT peak was above the 99th percentile and CAG less than 50% in all patients.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  1. Complete CMR during hospitalization;
  2. CAG results suggesting coronary stenosis of less than 50%;
  3. peak hsTnT above the 99th percentile.

Exclusion criteria

Exclusion Criteria:

  • CMR image sequences are missing or of poor quality.
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Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
387 participants (actual)
Patient registry
No

Groups and cohorts

  • diagnosed with MINOCA and completed with cardiac magnetic resonance

    Other: Cardiac MRI

Interventions

  • OtherCardiac MRI

    Patients with a diagnosis of MINOCA and completed CMR were included in this study

06

What researchers measure

Primary outcomes

  1. Primary endpoint events included any cause, non-fatal infarction, stroke, or cardiac readmission.

    Time frame: All patients were followed until June 30, 2024

07

Study locations

1 site
  • The Affiliated Hospital of Xuzhou Medical University
    Xuzhou, Jiangsu 221002, China
08

References and documents

Individual participant data

Plan to share: Undecided — Considering the patient's privacy and the next steps in our research program

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 16, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT06502899
Lead sponsor
The Affiliated Hospital of Xuzhou Medical University
Responsible party
Sponsor
First posted
Jul 16, 2024
Start date
Jan 1, 2019
Primary completion
Jun 30, 2024
Completion
Jul 9, 2024
Last update
Jul 16, 2024

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jul 2024. You cannot join it, but the record below documents what was studied.

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