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CompletedNCT06501014Updated Dec 10, 2025

Effectiveness of Action Observation Therapy in Stroke Patients

An interventional study of Action Observation Therapy-Experimental Group and Conventional Exercises-Control Group in Stroke and Rehabilitation, sponsored by KTO Karatay University. Completed at 1 site in Turkey (Türkiye). Open to participants aged 40 Years to 80 Years. Per ClinicalTrials.gov, last updated 2025-12-10.

Sponsored by KTO Karatay University · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
30
Allocation
Randomized
Ages
40 Years to 80 Years
Sex
All
01

Study summary

The goal of this clinical trial is to learn the effectiveness of action observation therapy in patients with stroke.

The main questions it aims to answer are:

Is action observation therapy an effective method in stroke patients?

Researchers will compare the results of two action observation-based exercises (home program) with conventional exercise to see whether action observation therapy works in the rehabilitation of stroke patients.

Participants:

Participants in one group will do action observation-based exercise (home plus conventional exercise for 24 sessions, Patients in the control group will only undergo conventional exercise in addition to routine treatment.

Read the detailed description

Individuals with chronic stroke will be included in this study. Participants will be randomly divided into two groups, and patients in both groups will continue their routine treatments.

Patients in the control group will only undergo conventional exercise. Patients in the study group will be given a home exercise program in addition to conventional treatment. However, patients will be asked to first watch the video of each exercise in this program and then perform the exercise.

Patients will be asked to perform the exercises 3 days a week for 8 weeks. Evaluations will be made twice, before the exercise program application begins and after the sessions are completed.

02

Conditions studied

  • Stroke
  • Rehabilitation

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03

In context

Stroke

7,286 studies on the registry are indexed under Stroke; 2,007 are open to participants now.

This study's enrollment of 30 is below the median of 50 across 5,369 interventional studies indexed under Stroke.

Browse Stroke studies →

Lead sponsor

KTO Karatay University is the lead sponsor of 126 studies on the registry; 16 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
40 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Stroke patients in the chronic phase (more than 6 months have passed since the stroke)
  • Patients over 40 years of age
  • Patients who can stand and walk independently (including those using walking aids)

Exclusion criteria

Exclusion Criteria:

  • Additional disease (neurological, orthopedic, etc.) that may affect motor performance and balance.
  • Patients with communication problems
  • Patients with mental problems (mini-mental test score \<23)
  • Patients aged 85 and over
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
30 participants (actual)

Study arms

  • Experimental
    Action Observation Therapy-Experimental Group

    Patients will be asked to watch the exercises before doing them. For each exercise, patients will first watch the relevant video and do the exercise after the video ends.

    Other: Action Observation Therapy-Experimental Group

  • Active comparator
    Conventional Exercises-Control Group

    Patients will be subjected to conventional exercise only.

    Other: Conventional Exercises-Control Group

Interventions

  • OtherAction Observation Therapy-Experimental Group

    Patients will be asked to watch the exercises before doing them.For each exercise, patients will first watch the relevant video and do the exercise after the video ends.

  • OtherConventional Exercises-Control Group

    Patients will be subjected to conventional exercise only.

06

What researchers measure

Primary outcomes

  1. 2 minute walk test

    Patients will be asked to walk 30 meters long on a flat surface for 2 minutes. When the time is up, the distance the patient can walk will be recorded.

    Time frame: The evaluation will be applied at the baseline and after study completion, an average of 2 months.

  2. Fugl-Meyer Assessment

    The FMA motor assessments for the lower extremity (minimum score:0 and maximum score 34 points) will be applied. A higher score means the patient's motor movements are better.

    Time frame: The evaluation will be applied at the baseline and after study completion, an average of 2 months.

  3. Berg Balance Scale

    The Berg Balance Scale is used to objectively determine a patient's ability (or inability) to safely balance during a series of predetermined tasks. It is a 14 item list with each item consisting of a five-point ordinal scale ranging from 0 to 4, with 0 indicating the lowest level of function and 4 the highest level of funcion.

    Time frame: The evaluation will be applied at the baseline and after study completion, an average of 2 months.

07

Study locations

1 site
  • KTO Karatay University
    Konya, Turkey (Türkiye)
08

References and documents

Publications

  • Karaca O, Tekin AN. Home-based action observation training improves walking performance, balance, and lower limb motor function in chronic stroke: a randomized controlled trial. Brain Inj. 2026;40(9):802-809. doi: 10.1080/02699052.2026.2675400. Epub 2026 May 19. PubMed 42157362 ↗

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 10, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06501014
Lead sponsor
KTO Karatay University
Responsible party
Sponsor
First posted
Jul 15, 2024
Start date
Jul 16, 2024
Primary completion
Sep 30, 2025
Completion
Sep 30, 2025
Last update
Dec 10, 2025

Study contacts

Osman Karaca, PhD
principal investigator · KTO Karatay University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Oct 2025. You cannot join it, but the record below documents what was studied.

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