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CompletedNCT06472167Updated Aug 18, 2026

Breathing Exercises on Lung Function

An interventional study of Breathing exercises in Breathing Exercises, sponsored by Mansoura University Hospital. Completed at 1 site in Egypt. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-08-18.

Sponsored by Mansoura University Hospital · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
100
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

aim of this study is to evaluate the efficacy of pulmonary rehabilitation program as a non-pharmacological treatment method to: Improve functional capacity as assessed by six-minute walking distance (6MWD) test. Improve dyspnea level as assessed by Medical Research Council (MRC) dyspnea scale. Improve pulmonary function tests and arterial blood gas.

Read the detailed description

Breathing exercises offer numerous benefits for individuals with chronic airway diseases, such as chronic obstructive pulmonary disease (COPD), asthma and bronchiectasis. These exercises help improve respiratory function, reduce symptoms, and enhance the overall quality of life.Techniques such as diaphragmatic breathing, incentive spirometer and pursed lip breathing help patients use their lungs more effectively. Breathing exercises can enhance lung function by increasing the efficiency of the respiratory muscles and improving ventilation. Asthma is a chronic inflammatory disorder of the airways classified as intermittent or persistent (mild, moderate or severe), according to the presence of diurnal and nocturnal symptoms, necessity of medication, frequency of exacerbation, physical activity limitations and pulmonary function. All of these symptoms deteriorate in the patient's quality of life and psychological well-being and restrict daily living physical activities (DLPA). Asthma symptoms experienced during daily living physical activities (DLPA) or the fear of triggering symptoms may keep asthmatic subjects from engaging in physical exercise, and the patients tend to be less physically active and less conditioned than healthy individuals. In addition, asthmatic patients have higher levels of anxiety and depression that have been shown to be associated with an increased number of exacerbations and the diagnosis of severe asthma. These psychosocial disorders can modify the respiratory breathing pattern, which leads to irregular breathing, frequent sighing, and predominant thoracic breathing. These irregular breathing patterns increase the number of respiratory (breathlessness, chest tightness and pain) and non-respiratory symptoms (anxiety, dizziness and fatigue). Recent Global Initiative for Chronic Obstructive Pulmonary Disease guidelines (GOLD) underline the importance of pulmonary rehabilitation (PR) as a part of an integrative multidisciplinary approach regardless of the stage of disease

02

Conditions studied

  • Breathing Exercises

Keywords

  • Breathing exercises
  • lung function
  • Chronic airway diseases
03

In context

Lead sponsor

Mansoura University Hospital is the lead sponsor of 50 studies on the registry; 7 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • The patients fulfilled the criteria for COPD: the presence of a post bronchodilator FEV1 \< 80% predicated together with an FEV1/FVC \<0.70confirm the presence of airflow limitation that is not fully reversible.
  • COPD patients ranging from mild to severe according to GOLD [stages I-IV].
  • Asthmatic patients receive medical treatment for at least 6 months; and clinically stable (i.e., no exacerbation or changes in medication for ≥30 days).
  • None of the individuals had been engaged in any exercise-training program before participating in the study.
  • Optimized medical therapy according to GOLD \& Global Initiative for Asthma (GINA)
  • Clinically stable COPD and asthmatic patients (not suffering from a recent respiratory tract infection).
  • All patients are Ex-smoker

Exclusion criteria

Exclusion Criteria:

  • Age \<18 years.
  • Pregnancy
  • Current Smokers
  • Patients that are incapable of exercising; unable to understand any questionnaire
  • Multiple co- morbidity (e.g., cardiovascular diseases, active cancer)
  • Neuromuscular disease as Myasthenia gravis, kypho-scoliosis
  • Diaphragmatic Paralysis (paralyzed diaphragm exhibiting abnormal paradoxical movement, i.e., moving in a cranial direction during inspiration).
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Investigator)
Enrollment
100 participants (actual)

Study arms

  • No intervention
    Chronic airway diseases treated by medication

    Chronic airway diseases treated by medication without breathing exercises

  • Active comparator
    Chronic airway diseases treated by medication with breathing exercises

    Chronic airway diseases treated by medication and breathing exercises

    Behavioral: Breathing exercises

Interventions

  • BehavioralBreathing exercises

    Breathing exercises as diaphragmatic breathing exercises and pursued lip breathing and incentive spirometry

    Also known as: Diaphragmatic Breathing exercise, Pursued lip breathing

06

What researchers measure

Primary outcomes

  1. Impact of breathing exercises on Forced expiratory volume on first second (FEV1) in liter

    Effect of Breathing exercises on lung function using spirometry

    Time frame: 6 months

  2. Impact of breathing exercises on Forced vital capacity (FVC) in liter

    Effect of Breathing exercises on lung function using spirometry

    Time frame: 6 months

07

Study locations

1 site
  • Mohamed AbdElmoniem
    Al Mansurah, 35516, Egypt
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 18, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT06472167
Lead sponsor
Mansoura University Hospital
Responsible party
Mohamed Abd Elmoniem Mohamed (Lecturer of chest medicine, Mansoura University Hospital) — Principal investigator
First posted
Jun 25, 2024
Start date
Jun 1, 2024
Primary completion
Aug 10, 2025
Completion
Dec 10, 2025
Last update
Aug 18, 2026

Study contacts

Mohamed AbdElmoniem
principal investigator · Lecturer of chest medicine faculty of medicine Mansoura university

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.

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