An observational study in Primary Dysmenorrhea, sponsored by Cairo University. Completed at 1 site in Egypt. Open to female participants aged 17 Years to 25 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-06-21.
Sponsored by Cairo University · Observational
This study was conducted to investigate the correlation between spinopelvic alignment and uterine dimensions in primary dysmenorrhea.
Primary dysmenorrhea (PD) is a common condition characterized by severe menstrual cramps and lower abdominal pain before or during menstruation, without any underlying pelvic pathology. It is highly prevalent among adolescents and young women, with 16% to 93% of adolescents and 70% to 90% of young women experiencing PD. The severe menstrual discomfort associated with PD often leads to absenteeism from school or work, with approximately one-third to half of individuals missing at least one day per menstrual cycle, and 5% to 14% experiencing more frequent absences.
While the exact etiology of PD is not fully understood, researchers have proposed a potential relationship between PD and musculoskeletal factors. One hypothesis suggests that abnormal pelvic and lumbar spine alignment, coupled with abdominal muscle spasms, may affect the positioning of the uterus, increasing the susceptibility to dysmenorrhea. Additionally, lumbar spine misalignment could potentially impact uterine blood supply through vasoconstriction, contributing to menstrual pain.
Spinal misalignment has been proposed as a possible underlying cause of PD, with some studies suggesting that manual therapy techniques may alleviate PD symptoms. Furthermore, a lack of coordination between the pelvic floor muscles and surrounding soft tissues has also been implicated as a potential causative factor. However, research investigating the relationship between PD and musculoskeletal factors remains limited, and further exploration of the biomechanical factors influencing the pelvic region is needed. Therefore, this study aimed to investigate the correlation between spinopelvic alignment and uterine dimensions in primary dysmenorrhea.
Cairo University is the lead sponsor of 4,909 studies on the registry; 1,445 are open to participants now.
Of its 37 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.
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A sample of 40 girls was recruited from undergraduate students at Faculty of Physical Therapy, Cairo University and actively participated in this research.
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Exclusion Criteria:
Females with Primary Dysmenorrhea
Other: Evaluating spinopelvic alignment parameters · Other: Measuring uterine dimensions
Females without Primary Dysmenorrhea
Other: Evaluating spinopelvic alignment parameters · Other: Measuring uterine dimensions
Evaluation of thoracic kyphosis, lumbar lordosis, pelvic tilt, and pelvic torsion
Measurement of corpus length, corpus width, cervix length, and cervix width
Kyphotic angle
It was measured by a 4D formetric device as the maximum degree of kyphotic curvature, specifically the angle formed between the upper inflection point adjacent to the vertebral prominence and the thoracic-lumbar inflection point.
Time frame: It was measured during the 2nd or 3rd days of menstruation for each participant in both groups.
Lordotic angle
It was measured by a 4D formetric device as the maximum lordotic angle, calculated as the angle formed between the surface tangents at the thoracic-lumbar inflection point and the lower lumbar-sacral inflection point.
Time frame: It was measured during the 2nd or 3rd days of menstruation for each participant in both groups.
Pelvic tilt
It was determined by a 4D formetric device as the vertical disparity in millimeters (mm) between the two lumbar dimples. A positive value signifies that the right dimple is positioned higher than the left, while a negative value indicates the reverse, all in relation to a horizontal reference line connecting both dimples within the measuring system.
Time frame: It was measured during the 2nd or 3rd days of menstruation for each participant in both groups.
Pelvic torsion
It was measured by a 4D formetric device within the frontal plane, this measurement represents the degree of rotation of the right sacral dimple relative to the left sacral dimple.
Time frame: It was measured during the 2nd or 3rd days of menstruation for each participant in both groups.
corpus length
It was measured by ultrasonography. The longitudinal axis of the uterine corpus was determined at a longitudinal plane where the internal cervical os and endometrium appeared at their tallest, measured from the projection point of the endometrium on the uterine corpus to the internal cervical os.
Time frame: It was measured during the 2nd or 3rd days of menstruation for each participant in both groups.
corpus width
It was measured by ultrasonography. The transverse axis of the uterine corpus was assessed at the same plane, positioned perpendicular to the longitudinal diameter of the uterine corpus where it exhibited its maximum width.
Time frame: It was measured during the 2nd or 3rd days of menstruation for each participant in both groups.
cervix length
It was measured by ultrasonography. t was measured as the distance between the internal cervical os and the external os.
Time frame: It was measured during the 2nd or 3rd days of menstruation for each participant in both groups.
cervix width
It was measured by ultrasonography. The measurement of the transverse diameter of the uterine cervix was conducted at its thickest section, oriented perpendicular to an imaginary line corresponding to the longitudinal measurement of the cervix.
Time frame: It was measured during the 2nd or 3rd days of menstruation for each participant in both groups.
Ran from Mar 2022 to primary completion in Feb 2023, 11 months.
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This study is completed, as verified in Jun 2024. You cannot join it, but the record below documents what was studied.
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