An observational study in Measles, sponsored by King's College London. Completed at 1 site in United Kingdom. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-05-06.
Sponsored by King's College London · Observational
Measles is a highly contagious disease which can result in severe complications in some patients. Healthcare workers have a higher risk of getting measles than the general population because of their increased risk of exposure from patients with measles attending hospitals. Having had measles in the past or at least one dose of the measles, mumps and rubella (MMR) vaccine provides protection (immunity) against measles. UK government guidelines therefore recommend that healthcare workers and non-clinical staff with direct patient contact are fully vaccinated or have other evidence of immunity. Yet, evidence from recent measles outbreaks suggests that some healthcare workers are not immune or do not know if they are immune, with implications for containment efforts, cost and transmission. The purpose of this study is to identify barriers and facilitators to uptake of the MMR vaccine among healthcare workers at King's College Hospital NHS Foundation Trust (KCH). KCH healthcare workers will be eligible to take part in the study if they are aged 18 and over and have direct contact with patients. In addition, the research will focus on four subgroups of healthcare workers at KCH: those who are not immune, those who have not completed the full vaccination schedule, those who don't know their immunity status, those received the vaccine only after joining KCH. The latter may provide insights into facilitators to vaccine uptake. Measles immunity forms part of the occupational health screening at KCH. A series of semi structured interviews lasting approximately 1 hour will explore participants' experiences of the occupational health vaccine screening process and measles vaccine campaigns at KCH; why they are unvaccinated/not fully vaccinated/do not know if they are immune/decided to be vaccinated after joining KCH; and what measures or interventions may help healthcare workers when deciding whether to get the MMR vaccine.
134 studies on the registry are indexed under Measles; 17 are open to participants now.
This study's enrollment of 23 is below the median of 282 across 26 observational studies indexed under Measles.
Browse Measles studies →King's College London is the lead sponsor of 520 studies on the registry; 126 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Participants will be recruited from a population of hospital-based healthcare workers, including doctors, nurses, health assistants, etc. Healthcare workers will be recruited from one site only (KCH).
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Healthcare workers at one Trust who have direct patient contact and fall within one of four groups: 1) they are not immune to measles (have not had measles in the past and have not been vaccinated with both doses of the MMR vaccine), 2) they have not completed the full vaccination schedule (they have received only 1 dose of the MMR vaccine), 3) they do not know their immunity status, and 4) they received the MMR vaccine after joining the Trust.
Biological: MMR vaccination
MMR vaccination status
Barriers to MMR vaccination
Barriers to MMR vaccination will be explored in the qualitative interview
Time frame: Collected at one timepoint 1 day during qualitative interview
Facilitators to MMR vaccination
Facilitators to MMR vaccination will be explored in the qualitative interview
Time frame: Collected at one timepoint 1 day during qualitative interview
Reasons for not knowing immunity status
Reasons for not knowing immunity status will be explored in the qualitative interview
Time frame: Collected at one timepoint 1 day during qualitative interview
Experiences of the occupational health vaccine screening process at KCH
Experiences of the occupational health vaccine screening process at the Trust will be explored in the qualitative interview
Time frame: Collected at one timepoint 1 day during qualitative interview
Plan to share: Undecided — Pseudonymised interview transcripts will be uploaded onto the King's College London Open Research Data System with the participant's consent.
No publications or documents are linked to this record.
Ran from Sep 2024 to primary completion in Dec 2024, 3 months.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Apr 2025. You cannot join it, but the record below documents what was studied.
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