A Phase 4 interventional study of Commercial measles, mumps, and rubella (MMR) vaccine in Heart Transplant Infection Prevention, sponsored by Children's Mercy Hospital Kansas City. Recruiting at 1 site in United States. Open to participants aged 1 Year to 17 Years. Per ClinicalTrials.gov, last updated 2026-09-24.
Sponsored by Children's Mercy Hospital Kansas City · Phase 4, Interventional, and Prevention
The study is an interventional, non-randomized assessment of safety and efficacy of live Measles, Mumps and Rubella (MMR) vaccine in subjects aged 12-months to 17 years who have undergone heart transplantation. Subjects who provide permission/assent will receive the commercial MMR vaccine according to product indication and labeling.
134 studies on the registry are indexed under Measles; 17 are open to participants now.
This study's planned enrollment of 60 is below the median of 852 across 105 interventional studies indexed under Measles.
Browse Measles studies →Children's Mercy Hospital Kansas City is the lead sponsor of 210 studies on the registry; 20 are open to participants now.
Of its 18 completed or terminated interventional studies of FDA-regulated products, 14 (78%) have results posted.
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Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
A weakened immune system. It can come from an illness, such as HIV or some blood cancers, or from medicines that turn the immune system down, for example after an organ transplant or for an autoimmune disease; steroids at higher doses count.
Read whether the line is about a condition or about medicines, and which medicines and doses it means.
Corticosteroids (steroids)
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Immunosuppression
A weakened immune system. It can come from an illness, such as HIV or some blood cancers, or from medicines that turn the immune system down, for example after an organ transplant or for an autoimmune disease; steroids at higher doses count.
Read whether the line is about a condition or about medicines, and which medicines and doses it means.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Patients receiving MMR vaccination due to no historical vaccine OR a seronegativity for measles
Drug: Commercial measles, mumps, and rubella (MMR) vaccine
Participants will receive the commercial MMR vaccine if they are deemed eligible for the study.
Number of participants who experience adverse reactions to the measles, mumps, and rubella vaccination
Patients will be screened for adverse reactions following vaccine administration
Time frame: Between 0-240 days after vaccine administration
Number of participants with resultant initial seropositivity against measles after vaccination
Serologic response will be measured after vaccine administration.
Time frame: Between 60-240 days after vaccine administration.
Number of participants who experience prolonged seropositivity after vaccine administration
Serologic response will be tested at least 365 days after final vaccine administration
Time frame: Minimum of 365 days after vaccine administration
Plan to share: Undecided
No publications or documents are linked to this record.
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