ClinicalTrials.gg
CompletedNCT06441058Updated Jan 27, 2026

Retrospective Database Study: Influence of Post-endodontic Restoration Placement on Survival of Root Canal-treated Teeth

An observational study in Root Canal Treatment, sponsored by University of Göttingen. Completed at 1 site in Germany. Per ClinicalTrials.gov, last updated 2026-01-27.

Sponsored by University of Göttingen · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
541
Sex
All
01

Study summary

The aim of this study is to assess the influence (i.e. type and timing) of post-endodontic restorations on the survival of root canal-treated teeth and to determine the influence of patient-, tooth-, treatment-, and restoration-specific parameters on longevity.

Patients who received a root-canal treatment between 1998 and 1999 with subsequent placement of an indirect restoration (e.g. crown, partial crown) will be retrospectively analyzed. Patient-, tooth-, treatment-, and restoration-specific parameters will be obtained from digital and paper-based dental records.

Survival and success of the root-canal treatments will be assessed using Kaplan-Meier statistics. Mean annual failure rates (mAFR) and median survival time will be calculated (Kaplan-Meier statistics). Potential predictive factors will be tested using log-rank tests and multi-variate Cox-regression analysis.

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Conditions studied

  • Root Canal Treatment
03

In context

Lead sponsor

University of Göttingen is the lead sponsor of 37 studies on the registry; 3 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients who received a root-canal treatment followed by the placement of an indirect post-endodontic restoration (e.g. partial crowns, crowns) within the Department of Preventive Dentistry, Periodontology and Cariology between 1998 and 1999.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patients who received a root-canal treatment followed by the placement of an indirect post-endodontic restoration (e.g. partial crowns, crowns) within the Department of Preventive Dentistry, Periodontology and Cariology between 1998 and 1999.

Exclusion criteria

Exclusion Criteria:

  • None.
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Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
541 participants (actual)
Patient registry
No

Groups and cohorts

  • Indirect post-endodontic restorations

    Indirect post-endodontic restorations (e.g. crown, partial crown).

    Other: No patient treatment is associated with the study

Interventions

  • OtherNo patient treatment is associated with the study

    No patient treatment is associated with the study.

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What researchers measure

Primary outcomes

  1. Success of endodontic treatment

    Success is defined as the time-interval without a subsequent endodontic re-intervention or extraction of the tooth.

    Time frame: 1998-2023

Secondary outcomes

  1. Survival of the tooth

    Survival of the tooth is defined as the time-interval without extraction of the tooth.

    Time frame: 1998-2023

07

Study locations

1 site
  • University Medical Center Göttingen, Dept. of Preventive Dentistry, Periodontology and Cariology
    Göttingen, Lower Saxony 37075, Germany
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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Ran from Jun 2024 to primary completion in Jun 2025, 12 months.

How these figures are worked out, and which studies are left out of them.

Registered
May 28, 2024
First posted
Jun 4, 2024
StartActual
Jun 1, 2024
Primary completionActual
Jun 1, 2025
CompletionActual
Jun 1, 2025
Last update
Jan 27, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Jan 27, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT06441058
Lead sponsor
University of Göttingen
Responsible party
Philipp Kanzow, Prof. Dr. med. dent., Dr. rer. medic. (Senior Lecturer, University Medical Center Goettingen) — Principal investigator
First posted
Jun 4, 2024
Start date
Jun 1, 2024
Primary completion
Jun 1, 2025
Completion
Jun 1, 2025
Last update
Jan 27, 2026

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jan 2026. You cannot join it, but the record below documents what was studied.

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