An observational study in Functional Movement Disorder, sponsored by Western University, Canada. Not yet recruiting at 1 site in Canada. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-01-24.
Sponsored by Western University, Canada · Observational
Passive thoughts also known as mind-wandering are the thoughts that are not produced from the current task. When we aren't focused on a task that needs our full attention, our minds tend to drift from one thought to another. It is believed that mind wandering is the baseline or natural state of the mind, and we shift our focus only when needed for a task. Many areas of the brain are active during mind-wandering, and these areas together are called the brain's default network. An important part of this network is the right temporoparietal junction.
Functional movement disorder (FMD) is characterized by unusual movements or walking difficulties that are not caused by a specific brain or nerve injury. Functional movement disorders are believed to be caused due to loss of sense of agency. The sense of agency is the awareness that one is responsible for their own actions. The brain network involved in the sense of agency is mainly located in the right side of the brain, especially in the right temporoparietal junction. In FMD patients, there is decreased connectivity between the right temporoparietal junction and other brain areas that control movement.
Since both passive thoughts (mind wandering) and the sense of agency involve the temporoparietal junction, and because the sense of agency is abnormal in functional movement disorders (FMD), we plan to study passive thoughts in individuals with FMD. The study aims to find out how passive thoughts differ between individuals with FMD and healthy individuals. Passive thoughts will be measured using Mind Excessively Wandering Scale (MEWS).
To evaluate passive thoughts in functional movement disorders (FMD), we will collect data from 30 FMD patients and 30 healthy controls. Patients will be recruited from the movement disorders clinic and the integrated functional movement disorders clinic at LHSC. Both groups will be asked to complete the paper-based Mind Excessively Wandering Scale (MEWS) to evaluate passive thoughts. Additionally, FMD patients will complete the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0), a 36-item self-administered questionnaire designed to measure disability over the past 30 days. Completing both questionnaires will take approximately 15-20 minutes. The questionnaires will be completed once.
89 studies on the registry are indexed under Conversion Disorder; 34 are open to participants now.
This study's planned enrollment of 60 is close to the median of 60 across 37 observational studies indexed under Conversion Disorder.
Browse Conversion Disorder studies →Western University, Canada is the lead sponsor of 224 studies on the registry; 56 are open to participants now.
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Patients diagnosed with a functional movement disorder will be included in the study.
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Exclusion criteria for cases:
The cases will complete the Mind Excessively Wandering Scale (MEWS) and World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0), a 36-item self-administered questionnaire. The individual responses will remain anonymous.
Other: Questionaire
The controls will complete the Mind Excessively Wandering Scale (MEWS). The individual responses will remain anonymous.
Other: Questionaire
The study will involve completing the Mind Excessively Wandering Scale (MEWS) and World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0), a 36-item self-administered questionnaire.
Passive thoughts questionnaire
The Passive Thoughts Questionnaire assesses the severity of passive thoughts and their impact on daily life.
Time frame: Day 1
Plan to share: No
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Start is estimated for Mar 2025; primary completion for Dec 2027, 33 months later.
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This study is not yet recruiting, as verified in Sep 2024. You cannot join it, but the record below documents what was studied.
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