An interventional study of retroclavicular block in Pain Management, sponsored by New Valley University. Recruiting at 1 site in Egypt. Open to participants aged 20 Years to 65 Years. Per ClinicalTrials.gov, last updated 2026-05-07.
Sponsored by New Valley University · Not applicable, Interventional, and Prevention
The retroclavicular (coracoid) approach for brachial plexus anesthesia is recognized for its facility and simplicity to perform .
The block has been well described in the anesthesia community since it was first introduced by Hebbard and Royse in 2007 . In 2017, Luftig . first described the block's use in the ED setting for a variety of indications . Because of its different needle entry point, the retro clavicular (RCB) approach offers an almost perpendicular needle-ultrasound (US) beam angle.
Regional anesthesia (RA) offers several advantages over general anesthesia (GA) for upper limb orthopedic surgery. One of the advantages is the improvement in postoperative pain, which leads to decreased use of postoperative opioids needs and reduces the recovery time for patients . A variety of approaches for regional blockade for upper extremity surgery have been described.
Dexamethasone is a corticosteroid drug that has been used as an adjuvant to reduce postoperative pain.
The use of peri neural dexamethasone (i.e. dexamethasone added to the local anesthesia solution) as an adjuvant to peripheral nerve block to improve analgesia provided by local anesthetic alone . Peri neural dexamethasone, as an adjuvant to peripheral nerve block, has been associated with faster onset of anesthesia , longer duration of anesthesia/analgesia decreased postoperative pain intensity and decreased postoperative analgesia requirements compared with local anaesthetic alone . The exact mechanism by which dexamethasone reduces pain is not known. The decrease in pain intensity and the prolonged analgesia attained with the use of perineural dexamethasone may be the result of a local, or systemic action, or both . Dexamethasone may act locally on glucocorticosteroid receptors to induce vasoconstriction, thereby decreasing systemic absorption of local anaesthetics . Other potential mechanisms of action include suppression of C-fibre transmission of pain signals and direct action on the nerve cell to reduce neural discharge . Dexamethasone may act systemically by reducing the inflammatory response caused by surgical tissue injury .
1,190 studies on the registry are indexed under Agnosia; 508 are open to participants now.
This study's planned enrollment of 80 is close to the median of 78 across 1,024 interventional studies indexed under Agnosia.
Browse Agnosia studies →New Valley University is the lead sponsor of 23 studies on the registry; 12 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
40patients received 40 ml of bupivacaine 0.25%(in total 100 mg)+1 ml of dexamethasone)
Other: retroclavicular block
: 40patients received. 40 ml of bupivacaine 0.25%(in total 100 mg)+1 ml saline
Other: retroclavicular block
regional anesthesia
sensory and motor duration of block
efficacy of block
Time frame: 24 hours
Plan to share: No
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