An interventional study of parenteral nutrition supplements and enteral nutrition supplements in Nutritional Support, Hepato-Biliary Neoplasm and Postoperative, sponsored by Karaganda Medical University. Completed at 1 site in Kazakhstan. Open to participants aged 20 Years to 75 Years. Per ClinicalTrials.gov, last updated 2024-05-02.
Sponsored by Karaganda Medical University · Not applicable, Interventional, and Other
A comprehensive comparative analysis of the effectiveness of isolated enteral, isolated parenteral and mixed type of nutritional support in the early postoperative period in patients after operations performed on the malignant neoplasms of hepatico-pancreatico-duodenal zone.
A prospective, longitudinal, parallel study and retrospective analysis of the results of treatment of 91 patients with malignant tumors of the hepatico-pancreato-duodenal zone who underwent the following operations:
The first group (n=31) included patients who received enteral nutrition (EN) after surgery. The second group (n=30) included patients who received parenteral nutrition (PN) and the third group (n=30) who received mixed nutrition (MN), as a variation of the partial parenteral nutrition technique, in the early postoperative period.
Some nutritional status indicators available for determination at the Oncology Clinic were assessed - body mass index (weight measurements were carried out before surgery, on the 5th, 10th and 15th days), basal metabolic rate (calculated using the Harris-Benedict equation, based on anthropometric data of the patient (gender, age, weight and height).), laboratory parameters: blood hemoglobin, lymphocytes, total protein, serum albumin, serum transferrin, total bilirubin and direct, alanine aminotransferase (ALT), aspartate aminotransferase (AST), which are related to the traditional method for assessing nutritional status
484 studies on the registry are indexed under Biliary Tract Neoplasms; 187 are open to participants now.
This study's enrollment of 91 is above the median of 56 across 404 interventional studies indexed under Biliary Tract Neoplasms.
Browse Biliary Tract Neoplasms studies →Karaganda Medical University is the lead sponsor of 10 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
female and male patients in age of 20-75 with malignant tumors of the hepato-pancreato-duodenal zone who have undergone any of the following operations:
Exclusion Criteria:
patients receiving enteral nutrition (EN) after surgery
Dietary Supplement: enteral nutrition supplements
patients receiving parenteral nutrition (PN)
Dietary Supplement: parenteral nutrition supplements
patients receiving mixed nutrition (MF)
Dietary Supplement: mixed nutrition supplements
parenteral nutrition
Also known as: parenteral nutrition
enteral nutrition
Also known as: enteral nutrition
mixed nutrition
Also known as: mixed nutrition
Number of Participants with changes of BMI in kg/m^2
Variables of Body mass index measured by Canadian Guidelines for Body Weight Classification in Adults
Time frame: Day 0, Day 5, Day 10, Day15
Basal Metabolic rate
basal metabolic rate according to the Harris-Benedict equation
Time frame: Day 0, Day 5, Day 10, Day15
Total protein level in Blood
Blood biochemical analysis: total protein in g/L
Time frame: Day 0, Day 5, Day 10, Day15
Serum albumin in g/L
Blood biochemical analysis: serum albumin in g/L
Time frame: Day 0, Day 5, Day 10, Day15
Serum transferrin in g/L
Blood biochemical analysis: serum transferrin in g/L
Time frame: Day 0, Day 5, Day 10, Day15
Total bilirubin in mmol/L
Blood biochemical analysis: total bilirubin in mmol/L
Time frame: Day 0, Day 5, Day 10, Day15
Direct bilirubin in mmol/L
Blood biochemical analysis: direct bilirubin in mmol/L
Time frame: Day 0, Day 5, Day 10, Day15
ALT in IU/L
Blood biochemical analysis: ALT in IU/L
Time frame: Day 0, Day 5, Day 10, Day15
AST in IU/L
Blood biochemical analysis: AST in IU/L
Time frame: Day 0, Day 5, Day 10, Day15
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This study is completed, as verified in Apr 2024. You cannot join it, but the record below documents what was studied.
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Karaganda Medical University