CClinicalTrials.gg
CompletedNCT06397170Updated Sep 19, 2024

Graded Repetitive Arm Supplementary Program Versus Task Based Training on Upper Limb Function in Stroke Patients

An interventional study of Graded repetitive arm supplementary program and Task based training in Stroke, Upper Extremity Paresis and Motor Activity, sponsored by Riphah International University. Completed at 1 site in Pakistan. Open to participants aged 40 Years to 60 Years. Per ClinicalTrials.gov, last updated 2024-09-19.

Sponsored by Riphah International University · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
38
Allocation
Randomized
Ages
40 Years to 60 Years
Sex
All
01

Study summary

To determine effects of graded repetitive arm supplementary program versus Task based training on Upper limb function in stroke patients.

Read the detailed description

This study will be Randomized Clinical Trial. A total of 38 stroke patients will be recruited by using non-probability convenience sampling Technique. Patients will be Randomized and allocated into two interventional groups based on the inclusion and exclusion criteria. Patients in Group A will receive Graded repetitive arm supplementary program and Patients in Group B will receive Task based training. All participants will receive the treatment for 40 minutes per session, 5 days per week for 5 weeks. For the evaluation of all participant scales like be Chedoke Arm and Hand Activity Inventory for clinical relevance, Fugl Mayer assessment scale for performance assessment, Action Reach Arm Test for coordination and dexterity and Motor Activity Log for functional assessment of Upper limb in stroke patients. D

02

Conditions studied

  • Stroke
  • Upper Extremity Paresis
  • Motor Activity

Keywords

  • Stroke
  • Upper Extremity Paresis
  • Motor Activity
03

In context

Muscle Weakness

601 studies on the registry are indexed under Muscle Weakness; 99 are open to participants now.

This study's enrollment of 38 is below the median of 46 across 444 interventional studies indexed under Muscle Weakness.

Browse Muscle Weakness studies →

Lead sponsor

Riphah International University is the lead sponsor of 2,133 studies on the registry; 633 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
40 Years to 60 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Patients with Sub acute stage of stroke.
  • Patients with Ischemic and Haemorrhagic stroke.
  • Patients with Cognition level on Mini Mental State Examination must be > 24
  • Patients with mild pain in upper extremity according to Numeric Pain Rating Scale
  • Patients with Grade 2 active movements in affected extremity Tone of upper limb at Modified Ashworth Scale Grade 1+.

Exclusion criteria

Exclusion Criteria:

  • Other neurological disorders e.g. brain tumor, encephalitis, meningitis, brain abscess.
  • Use of antipsychotics
  • Use of drugs for spasticity.
  • Patients with vestibular impairment.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
38 participants (actual)

Study arms

  • Experimental
    Graded repetitive arm supplementary program group

    Patients in Group A will receive Graded repetitive arm supplementary program.

    Other: Graded repetitive arm supplementary program

  • Active comparator
    Task based training group

    Patients in Group B will receive Task based training.

    Other: Task based training

Interventions

  • OtherGraded repetitive arm supplementary program

    Patients in Group A will receive Graded repetitive arm supplementary program

  • OtherTask based training

    Patients in Group B will receive Task based training.

06

What researchers measure

Primary outcomes

  1. Fugl Mayer assessment scale

    It is designed to assess reflex activity, movement control and muscle strength in the upper extremity of people with post-stroke hemiplegia. total score is 126.This tool has an excellent Inter- and intrarater reliability (intra class correlation coefficient = 0.98-0.99), validity is also excellent (r = 0.74-0.93, P \< .0001). Higher scores indicate maximum recovery. higher the score greater is the improvement

    Time frame: 6 months

  2. The Motor Activity Log (MAL)

    The Motor Activity Log (MAL) is a subjective outcome measure of an individual's real life functional upper limb performance. The Motor activity log is administered by semi-structured interview and items are scored by patients according to their performance of each task over the past 7 days. The MAL adopts a 6-point ordinal scale, although patients can attribute a half-score, resulting in 11-point Likert scales with specified anchoring definitions at 6 points. higher the score greater is the improvement

    Time frame: 6 months

07

Study locations

1 site
  • Imran International Amjad
    Islamabad, Punjab 44000, Pakistan
08

References and documents

Publications

  • Connell LA, McMahon NE, Watkins CL, Eng JJ. Therapists' use of the Graded Repetitive Arm Supplementary Program (GRASP) intervention: a practice implementation survey study. Phys Ther. 2014 May;94(5):632-43. doi: 10.2522/ptj.20130240. Epub 2014 Feb 6. PubMed 24505098 ↗
  • Veerbeek JM, van Wegen E, van Peppen R, van der Wees PJ, Hendriks E, Rietberg M, Kwakkel G. What is the evidence for physical therapy poststroke? A systematic review and meta-analysis. PLoS One. 2014 Feb 4;9(2):e87987. doi: 10.1371/journal.pone.0087987. eCollection 2014. PubMed 24505342 ↗
  • Yang CL, Waterson S, Eng JJ. Implementation and Evaluation of the Virtual Graded Repetitive Arm Supplementary Program (GRASP) for Individuals With Stroke During the COVID-19 Pandemic and Beyond. Phys Ther. 2021 Jun 1;101(6):pzab083. doi: 10.1093/ptj/pzab083. PubMed 33682872 ↗
  • Lee HS, Lim JH, Jeon BH, Song CS. Non-immersive Virtual Reality Rehabilitation Applied to a Task-oriented Approach for Stroke Patients: A Randomized Controlled Trial. Restor Neurol Neurosci. 2020;38(2):165-172. doi: 10.3233/RNN-190975. PubMed 32176674 ↗

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 19, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06397170
Lead sponsor
Riphah International University
Responsible party
Sponsor
First posted
May 2, 2024
Start date
May 1, 2024
Primary completion
Sep 1, 2024
Completion
Sep 1, 2024
Last update
Sep 19, 2024

Study contacts

Zeest hashmi
principal investigator · Riphah International University

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Sep 2024. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion