An interventional study of Smartphone App-delivered Smoking Cessation Intervention and Smartphone App-delivered Smoking Cessation Intervention in Cigarette Smoking-Related Carcinoma, sponsored by Fred Hutchinson Cancer Center. Withdrawn at 1 site in United States. Open to participants aged 18 Years to 30 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-10-08.
Sponsored by Fred Hutchinson Cancer Center · Not applicable, Interventional, and Prevention
This clinical trial assesses the acceptability and efficacy of Empowered, Queer, Quitting, and Living--New Mexico (EQQUAL-NM), a smoking cessation intervention for sexual and gender minority young adults in New Mexico. Smoking prevalence among sexual and gender minority (SGM) adults in New Mexico is more than twice as high as non-SGM adults. Helping young adult tobacco users to quit is critical, yet there have been few efforts to develop tailored treatments specifically for this population. EQQUAL-NM is a digital smoking cessation intervention designed specifically for SGM young adult smokers in New Mexico and may help them quit smoking.
OUTLINE:
Participants are randomized to 1 of 2 groups.
GROUP I: Participants receive access to a self-guided, smartphone app-delivered quit smoking program, called EQQUAL-NM (Program A) that helps explore personal values and teaches participants about smoking triggers and skills to help them manage cravings and accept thoughts and feelings related to smoking. Participants receive text message reminders and prompts on study. Some participants also undergo collection of a saliva sample during follow-up.
GROUP II: Participants receive access to a self-guided, smartphone app-delivered quit smoking program, called EQQUAL-NM (Program B) that is based on current clinical practice guidelines for tobacco cessation to help them quit smoking. This program helps with quit advice, tracking progress on quitting smoking, and managing cravings. Participants receive text message reminders and prompts on study. Some participants also undergo collection of a saliva sample during follow-up.
After completion of study intervention, patients are followed up at 3 months.
Fred Hutchinson Cancer Center is the lead sponsor of 537 studies on the registry; 79 are open to participants now.
Of its 57 completed or terminated interventional studies of FDA-regulated products, 45 (79%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Participants receive self-guided smartphone app-delivered EQQUAL-NM (Program A) intervention on study. Participants also receive motivational messages, reminders and smoking cessation information via text messages. Some participants also complete at-home saliva sample collection during follow-up.
Behavioral: Smartphone App-delivered Smoking Cessation Intervention · Other: Health Promotion and Education · Other: Biospecimen Collection · Other: Questionnaire Administration
Participants receive self-guided smartphone app-delivered EQQUAL-NM (Program B) intervention on study. Participants also receive motivational messages, reminders and smoking cessation information via text messages. Some participants also complete at-home saliva sample collection during follow-up.
Behavioral: Smartphone App-delivered Smoking Cessation Intervention · Other: Health Promotion and Education · Other: Biospecimen Collection · Other: Questionnaire Administration
Receive access to EQQUAL-NM (Program A) intervention
Also known as: Smoking and Tobacco Use Cessation Intervention
Receive access to EQQUAL-NM (Program B) intervention
Also known as: Smoking and Tobacco Use Cessation Intervention
Receive text message reminders, motivational messages and prompts via SMS text messages (Program A)
Also known as: Text Message-Based Intervention
Receive text message reminders, motivational messages and prompts via SMS text messages (Program B)
Also known as: Text Message-Based Intervention
Complete at-home saliva sample collection
Also known as: Saliva Sample Collection
Ancillary studies
Participant satisfaction
Self-report of satisfaction overall and with specific program components will be rated on a 5-point Likert-type scale. Higher scale scores indicate higher satisfaction with the app.
Time frame: At 3-month follow-up
Number of logins to the assigned application
Server-recorded number of app openings over 3 months
Time frame: Up to 3-month follow-up
Self-reported 7-day point prevalence abstinence (PPA) from all nicotine and tobacco products
Self-report of no nicotine/tobacco product use over the previous 7 days, with the exception of FDA-approved medications
Time frame: At 3 months
Biochemically confirmed 7-day point prevalence abstinence (PPA) from all nicotine/tobacco products
Self-report of no nicotine/tobacco product use over the previous 7 days, with the exception of FDA-approved medications, biochemically confirmed via saliva cotinine
Time frame: At 3 months
Self-reported 30-day PPA from all nicotine/tobacco products
Self-report of no nicotine/tobacco product use over the previous 30 days, with the exception of FDA-approved medications
Time frame: At 3 months
Biochemically confirmed 30-day PPA from all nicotine/tobacco products
Self-report of no nicotine/tobacco product use over the previous 30 days, with the exception of FDA-approved medications, biochemically confirmed via saliva cotinine
Time frame: At 3 months
Self-reported 7-day PPA from cigarette smoking
Self-report of no cigarette smoking over the previous 7 days
Time frame: At 3 months
Self-reported 30-day PPA from cigarette smoking
Self-report of no cigarette smoking over the previous 30 days
Time frame: At 3 months
Change in Contemplation Ladder scores
Contemplation Ladder scores will be used to assess readiness to quit using cigarettes. Ladder scores are on a 0 to 10 scale, with higher change scores meaning greater increases readiness to quit.
Time frame: At baseline and at 3-month follow-up
Change in acceptance of tobacco-use triggers
Change in acceptance of tobacco-use triggers will be measured using the Avoidance and Inflexibility Scale. Higher change scores indicate greater improvement in acceptance of tobacco use triggers.
Time frame: At baseline and at 3-month follow-up
Change in values-guided action
Change in values-guided action measured using the Values Questionnaire. Higher change scores indicate greater improvement in values-guided action.
Time frame: At baseline and at 3-month follow-up
Plan to share: No
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This study is withdrawn, as verified in Apr 2025. You cannot join it, but the record below documents what was studied.
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