An observational study in Aortic Aneurysm, sponsored by University Hospital Augsburg. Recruiting at 1 site in Germany. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2024-04-15.
Sponsored by University Hospital Augsburg · Observational
It is currently unclear what activities aneurysms are involved in at the time of rupture. The aim of the study is to determine the activity performed at the time of aneurysm rupture.
The scientifically proven risk factors that significantly favor the rupture of an aortic aneurysm are female gender, the maximum diameter of the aortic aneurysm and the patient's current smoking status.
However, no analysis of the occupation performed at the time of aortic rupture of an abdominal aortic aneurysm has yet been carried out.
High arterial systolic blood pressure can promote aortic rupture. Blood pressure peaks can occur during physical exertion, for example when lifting heavy loads or during defecation.
Patients with an existing intact aortic aneurysm are currently advised to avoid such behaviors as a preventive measure. This includes, among other things, the practice of strength training or certain types of sport. This can subsequently lead to a reduction in quality of life, although this cannot currently be substantiated by scientific data. There is also no current guideline recommendation in this regard.
Furthermore, the role of stress and / or emotionally stressful events in connection with the occurrence of aortic ruptures has not yet been recorded in the literature. There is work on this in connection with aortic dissections, which postulates that an increase in emotional or psychological stress can lead to acute hypertension, which can cause a previously damaged aorta to rupture. A similar pathomechanism would also be conceivable for the rupture of aortic aneurysms.
There are indications that, in addition to gender-specific differences in the occurrence of aortic ruptures, there is also a different risk of rupture based on certain pre-existing conditions, dietary habits and age.
959 studies on the registry are indexed under Aneurysm; 174 are open to participants now.
This study's planned enrollment of 500 is above the median of 151 across 443 observational studies indexed under Aneurysm.
Browse Aneurysm studies →University Hospital Augsburg is the lead sponsor of 24 studies on the registry; 17 are open to participants now.
Counted across the registry records on this site, refreshed daily.
All patients with ruptured aortic aneurysm in Augsburg University Hospital form 01/01/24 till 12/31/29 for the prospecitve part of the trial.
All patients who have been treated for a ruptured aortic aneurysm in Augsburg University Hospital form 01/01/13 till 12/31/23 for the retrospectitve part of the trial.
Exclusion Criteria:
Questionnaire and patient interview, diary for day of rupture and the three previous days
Occupation at the time of the aortic aneurysm rupture
Occupation at the time of the aortic aneurysm rupture
Time frame: Occupation at the day of the aortic rupture and the three days prior
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University Hospital Augsburg