CClinicalTrials.gg
CompletedNCT06356337Updated Oct 14, 2025

A Light Exposure Tracker Designed to Improve Circadian Rhythms - Aim 1

An interventional study of Light goggles and Daily reminder test message in Alzheimer's Disease and Mild Cognitive Impairment, sponsored by Icahn School of Medicine at Mount Sinai. Completed at 1 site in United States. Open to participants aged 55 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-10-14.

Sponsored by Icahn School of Medicine at Mount Sinai · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
20
Allocation
Randomized
Ages
55 Years and older
Sex
All
01

Study summary

The purpose of this research study is to investigate the relationship between reminder messages sent via text and compliance with a daily morning light intervention designed to advance the circadian clock. Twenty healthy adults will be recruited to participate in a randomized, cross-over study where daily messages are, or are not, provided to remind participants to carry out the intervention.

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Conditions studied

  • Alzheimer's Disease
  • Mild Cognitive Impairment
03

In context

Alzheimer Disease

3,678 studies on the registry are indexed under Alzheimer Disease; 872 are open to participants now.

This study's enrollment of 20 is below the median of 70 across 2,808 interventional studies indexed under Alzheimer Disease.

Browse Alzheimer Disease studies →

Lead sponsor

Icahn School of Medicine at Mount Sinai is the lead sponsor of 764 studies on the registry; 181 are open to participants now.

Of its 121 completed or terminated interventional studies of FDA-regulated products, 82 (68%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
55 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • healthy adults over the age of 55
  • score of 25 or greater on MoCA

Exclusion criteria

Exclusion Criteria:

  • Severe sleep apnea
  • restless leg syndrome
  • obstructing cataracts
  • macular degeneration
  • diabetic retinopathy
  • glaucoma
  • use of sleep medications
  • brain disease
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Crossover assignment
Masking
Single (Participant)
Enrollment
20 participants (actual)

Study arms

  • Active comparator
    Light Googles plus reminder text messages

    Participants use green light goggles for one hour each morning for two consecutive weeks and also receive a daily text message reminding them to wear the light goggles

    Device: Light goggles · Behavioral: Daily reminder test message

  • Experimental
    Light Goggles alone

    Participants use green light goggles for one hour each morning for two consecutive weeks

    Device: Light goggles

Interventions

  • DeviceLight goggles

    Green light goggles worn for 1 hour each morning for two weeks

  • BehavioralDaily reminder test message

    Participants will receive daily text message reminding them to use light goggles each morning

06

What researchers measure

Primary outcomes

  1. Saliva samples for melatonin levels

    Serial saliva samples will be collected to calculate dim light melatonin onset.

    Time frame: Baseline and 2-weeks post-intervention for each Arm

Secondary outcomes

  1. Light exposure using the Speck

    The Speck light meter will be used to collect overall light exposure.The Speck light meter uses a photosensor to measure the amount of light study participants are exposed to each day.

    Time frame: worn all 12 study weeks

  2. Sleep time using actigraphy

    Sleep time will be calculated from the actigraph. The wrist actigraph measures activity during the day and how well you sleep at night. The actigraph software will calculate the amount of time spent in bed sleeping.

    Time frame: worn all 12 study weeks

07

Study locations

1 site
  • Light and Health Research Center
    Menands, New York 12204, United States
08

References and documents

Individual participant data

Plan to share: No — overall study results will be shared not individual.

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Oct 14, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT06356337
Lead sponsor
Icahn School of Medicine at Mount Sinai
Responsible party
Mariana Figueiro (Professor, Icahn School of Medicine at Mount Sinai) — Principal investigator
First posted
Apr 10, 2024
Start date
Feb 22, 2024
Primary completion
Aug 15, 2024
Completion
Aug 15, 2024
Last update
Oct 14, 2025

Study contacts

Mariana Figueiro, PhD
principal investigator · Ichan School of Medicine

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Oct 2025. You cannot join it, but the record below documents what was studied.

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