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CompletedNCT06339073Updated Apr 1, 2024

CT-based Model for Predicting Prolonged Weaning in Patients With Abdominal Trauma

An observational study in Wounds and Injuries and Ventilation Therapy; Complications, sponsored by Jinling Hospital, China. Completed at 1 site in China. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2024-04-01.

Sponsored by Jinling Hospital, China · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
1,023
Ages
18 Years and older
Sex
All
01

Study summary

Critically ill patients often require tracheal intubation for mechanical ventilation, and timely weaning is crucial for airway management and reducing complications. However, there is currently a lack of an effective tool to predict weaning time in critically ill patients. This retrospective study established an effective nomogram model for predicting the time of weaning from mechanical ventilation in abdominal trauma patients by considering multiple perspectives. The model has been validated and demonstrated good performance in terms of discrimination, calibration, and clinical utility. Moreover, the model can effectively predict the prognosis of critically ill patients. The findings of this study have important implications for guiding respiratory management in clinically critically ill patients, particularly trauma patients.

02

Conditions studied

  • Wounds and Injuries
  • Ventilation Therapy; Complications

Keywords

  • computed tomography
  • prolonged weaning
  • ventilation
  • trauma
03

In context

Wounds and Injuries

5,056 studies on the registry are indexed under Wounds and Injuries; 861 are open to participants now.

This study's enrollment of 1,023 is above the median of 135 across 1,597 observational studies indexed under Wounds and Injuries.

Browse Wounds and Injuries studies →

Lead sponsor

Jinling Hospital, China is the lead sponsor of 126 studies on the registry; 34 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Sampling method
Non-probability sample

Study population

Patients with abdominal trauma admitted to the General Surgical Department of Jinling Hospital from January 2010 to April 2023 were screened for eligibility.

Inclusion criteria

  • (1) with information on survival status and time;
  • (2) aged 18-80 years;
  • (3) admitted to ICU;
  • (4) with abdominal CT performed within 1-week post-trauma;
  • (5) use of mechanical ventilation.

Exclusion criteria

Exclusion Criteria:

  • (1) low-quality CT images;
  • (2) history of mental illness.
05

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
1,023 participants (actual)
Patient registry
No

Interventions

  • Devicemechanical ventilation

    Abdominal trauma patients were treated with mechanical ventilation according to their conditions.

06

What researchers measure

Primary outcomes

  1. Prolonged mechanical ventilation

    Prolonged mechanical ventilation was defined as length of mechanical ventilation \>7 days

    Time frame: through whole hospitalization of each participant, an average of 25 days

07

Study locations

1 site
  • the General Surgical Department of Jinling Hospital
    Nanjing, Jiangsu 210002, China
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 1, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT06339073
Lead sponsor
Jinling Hospital, China
Responsible party
Fengchan Xi (Chief of the Department of Intensive Care Unit, Associate chiefphysician, Nanjing Maternity and Child Health Care Hospital) — Principal investigator
First posted
Apr 1, 2024
Start date
Oct 1, 2023
Primary completion
Dec 15, 2023
Completion
Feb 5, 2024
Last update
Apr 1, 2024

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Mar 2024. You cannot join it, but the record below documents what was studied.

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