An interventional study of ELISA in Gestational Diabetes, sponsored by Benha University. Completed at 1 site in Egypt. Open to female participants aged 22 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-03-28.
Sponsored by Benha University · Not applicable, Interventional, and Diagnostic
Gestational diabetes mellitus (GDM) is the development of glucose intolerance (GI) during pregnancy in a previously normoglycemic (NG) woman and associated with insulin resistance (IR). GDM is the most prevalent metabolic disorder during pregnancy and became a major public health problem for being usually diagnosed and detected after 24 gestational weeks (GW), while its complications can occur much earlier and this may explain its burden on maternal and fetal welfare. Human zonulin is a surrogate marker of intestinal permeability and can be utilized as biomarker for intestinal barrier function. Zonulin-mediated increase in intestinal permeability plays a role in the pathogenesis of insulin resistance, obesity, DM and metabolic syndrome. The increasing global prevalence of GDM with its associated risk of poor pregnancy and long-term risks for the mother and the offspring may lead to the production of new generation of diabetics.
842 studies on the registry are indexed under Diabetes, Gestational; 198 are open to participants now.
This study's enrollment of 70 is below the median of 110 across 550 interventional studies indexed under Diabetes, Gestational.
Browse Diabetes, Gestational studies →Benha University is the lead sponsor of 356 studies on the registry; 68 are open to participants now.
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Exclusion Criteria:
Diagnostic Test: ELISA
Estimation of Zonulin by ELISA from the Blood samples which were obtained at time of pregnancy .
Estimation of Gestational DM
Relation between Serum Zonulin levels and Gestational Diabetes Mellitus
Time frame: 8 months
This study is completed, as verified in Mar 2024. You cannot join it, but the record below documents what was studied.
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Benha University