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RecruitingNCT06331351Updated Feb 9, 2026

Effect of Jing Si Herbal Tea Liquid Packets on Chronic Pharyngolaryngitis

An interventional study of control group and Jing Si herbal tea liquid packets in Chronic Pharyngitis, sponsored by Dalin Tzu Chi General Hospital. Recruiting at 1 site in Taiwan. Open to participants aged 20 Years to 70 Years. Per ClinicalTrials.gov, last updated 2026-02-09.

Sponsored by Dalin Tzu Chi General Hospital · Not applicable, Interventional, and Other

From the registry’s dates

  • Started Feb 2024; still recruiting 2 years 8 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
120
Allocation
Randomized
Ages
20 Years to 70 Years
Sex
All
01

Study summary

Chronic pharyngolaryngitis is common and often make people suffer in many aspects. The etiology is numerous, for example, airway hypersensitivity, gastroesophageal acid regurgitation, sicca syndrome, anxiety, etc.

The investigators aimed to investigate the effect of Jing Si herbal tea liquid packets on chronic pharyngolaryngitis by a design of randomized, double-blind clinical trial in this study. The subjects who were bed-ridden, without self-care ability, receiving hemodialysis, no idea about the details of this study, poor compliance for this study, alcohol and/or drugs additives, pregnancy and breast-feeding women were excluded from this study.

A questionnaire for health and habits was performed at the start of the study, and a questionnaire for Reflux Symptom Index (RSI) was performed at the start and the end of the study. Finally, Student's t-test was used to test the difference between the Jing Si herbal tea group and the control group. And, multivariate linear regression was used to test the violation of clinical factors on the treatment outcome of Jing Si herbal tea liquid packets on chronic pharyngolaryngitis.

Read the detailed description

Chronic pharyngolaryngitis is common and often make people suffer in many aspects. The etiology is numerous, for example, airway hypersensitivity, gastroesophageal acid regurgitation, sicca syndrome, anxiety, etc.

The investigators aimed to investigate the effect of Jing Si herbal tea liquid packets on chronic pharyngolaryngitis by a design of randomized, double-blind clinical trial in this study. One hundred and twenty adults of both sex with a range of age between of 20-70 years old were included. All participants were divided randomly into two groups. Jing Si herbal tea group received 1 pack of Jing Si herbal tea liquid packet twice a day for 1 month (30 days), and the control group received 1 pack of control liquid packet twice a day for 1 month (30 days). The subjects who were bed-ridden, without self-care ability, receiving hemodialysis, no idea about the details of this study, poor compliance for this study, alcohol and/or drugs additives, pregnancy and breast-feeding women were excluded from this study.

A questionnaire for health and habits was performed at the start of the study, and a questionnaire for Reflux Symptom Index (RSI) was performed at the start and the end of the study. Finally, Student's t-test was used to test the difference between the Jing Si herbal tea group and the control group. And, multivariate linear regression was used to test the violation of clinical factors on the treatment outcome of Jing Si herbal tea liquid packets on chronic pharyngolaryngitis.

02

Conditions studied

  • Chronic Pharyngitis

Keywords

  • Chronic pharyngitis
  • Jing Si herbal tea liquid packets
  • clinical trial
03

In context

Lead sponsor

Dalin Tzu Chi General Hospital is the lead sponsor of 37 studies on the registry; 6 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 70 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  1. Adult men and women aged 20 to 70 years old.
  2. Patients with chronic pharyngitis

Exclusion criteria

Exclusion Criteria:

  1. Patients who are bedridden or unable to take care of themselves.
  2. Dialysis patients.
  3. Patients who cannot understand the details of this study or cannot cooperate with the examination.
  4. History of alcohol or drug abuse.
  5. Pregnant and lactating women
05

Study design

Phase
Not applicable
Primary purpose
Other
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Care provider)
Enrollment
120 participants (estimated)

Study arms

  • Placebo comparator
    control group

    placebo: 2 times a day, 1 sachet each time.

    Other: control group

  • Experimental
    Jing Si herbal tea liquid packets group

    Jing Si herbal tea liquid packets: 2 times a day, 1 sachet each time.

    Other: Jing Si herbal tea liquid packets

Interventions

  • Othercontrol group

    2 times a day, 1 sachet each time.

    Also known as: Placebo

  • OtherJing Si herbal tea liquid packets

    2 times a day, 1 sachet each time.

06

What researchers measure

Primary outcomes

  1. Health questionnaire

    the recording items are as follows: age, gender, height, weight, waist circumference, disease history, smoking or not (quantification), drinking or not (quantification), and eating betel nut or not (quantification) , sleeping status, whether to drink coffee (quantification)

    Time frame: Before the test begins and after intervention completed (at 1 month)

  2. Reflux Symptom Index (RSI)

    The Reflux Symptom Index (RSI) is in common use as a semi-quantitative tool to assess symptoms associated with laryngopharyngeal reflux (LPR). RSI is a scoring tool that consists of nine items used to assess various symptoms associated with LPR. Each item has a scale ranging from zero (no complaints) to five (severe complaints), with a maximum of 45 indicating the most severe symptoms.

    Time frame: Before the test begins and after intervention completed (at 1 month)

07

Study locations

1 of 1 sites recruiting
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Started Feb 2024 (actual). Primary completion is estimated for Oct 2026, 32 months after the start.

How these figures are worked out, and which studies are left out of them.

Registered
Mar 8, 2024
First posted
Mar 26, 2024
StartActual
Feb 22, 2024
Primary completionEst.
Oct 31, 2026
CompletionEst.
Dec 31, 2026
Last update
Feb 9, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Feb 9, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06331351
Lead sponsor
Dalin Tzu Chi General Hospital
Responsible party
Sponsor
First posted
Mar 26, 2024
Start date
Feb 22, 2024
Primary completion
Oct 31, 2026 (estimated)
Completion
Dec 31, 2026 (estimated)
Last update
Feb 9, 2026

Study contacts

Juen-Haur Hwang, MD, PhD
Contact
g120796@tzuchi.com.tw
+886-5-2648000 ext. 5239
Juen-Haur Hwang, MD, PhD
study chair · Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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