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Not yet recruitingNCT06323798Updated Mar 21, 2024

Diffusion Weighted MRI Enables Differential Diagnosis Between Pyocele and Mucocele

An observational study in Pyocele; Sinus, sponsored by Central Hospital, Nancy, France. Not yet recruiting. Open to participants aged 18 Years to 99 Years. Per ClinicalTrials.gov, last updated 2024-03-21.

Sponsored by Central Hospital, Nancy, France · Observational

From the registry’s dates

  • Primary completion was expected by Jul 2024, 2 years 2 months ago, but the record still lists the study as not yet recruiting.
Study type
Observational
Model
Case-control
Time perspective
Retrospective
Enrollment
20
Ages
18 Years to 99 Years
Sex
All
01

Study summary

Diffusion MRI should allow for differentation of pus and simple retention in the paranasal sinuses, but this remained to be determined

Read the detailed description

On the basis of the apparent diffusion coefficient, the content of a para nasal sinus could be defined as simple mucus or pus. This differentiation is very important for the clinician for prompt treatment. The aim of this study is to retrospectively measure this coefficient and to correlate it to clinica data.

02

Conditions studied

  • Pyocele; Sinus

Keywords

  • sinus, pyocele, mri
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In context

Lead sponsor

Central Hospital, Nancy, France is the lead sponsor of 778 studies on the registry; 183 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 99 Years
Sexes eligible
All
Sampling method
Non-probability sample

Study population

patients with paranasal MRI

Inclusion criteria

  • paranasal sinus MRI with a diffusion weighted sequence

Exclusion criteria

Exclusion Criteria:

  • no clinical examination available
  • no bateriologic sample available
05

Study design

Observational model
Case-control
Time perspective
Retrospective
Enrollment
20 participants (estimated)
Patient registry
No

Groups and cohorts

  • cases

    patients with a paranasal sinus mri and a confirmed pyocele at bacteriologic sample reviewed in the medical file

    Diagnostic Test: MRI

  • controls

    patients with a paranasal sinus mri and a confirmed simple retention mucus at bacteriologic sample reviewed in the medical file

    Diagnostic Test: MRI

Interventions

  • Diagnostic testMRI

    Standard paranasal sinus MRI

06

What researchers measure

Primary outcomes

  1. apparent diffusion coefficient

    apparent diffusion coefficient on a diffusion weighted MRI sequence

    Time frame: 5 years

07

Study locations

No study locations are listed for this record.

08

References and documents

Publications

  • Radulesco T, Scemama U, Mancini J, Moulin G, Dessi P, Michel J, Varoquaux A. Role of diffusion-weighted imaging in the discrimination of purulent intrasinusal content: A retrospective study. Clin Otolaryngol. 2019 Sep;44(5):762-769. doi: 10.1111/coa.13388. Epub 2019 Jul 23. PubMed 31169984 ↗

Individual participant data

Plan to share: No — MRI is the proprety of the patient

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 21, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06323798
Lead sponsor
Central Hospital, Nancy, France
Responsible party
Sponsor
First posted
Mar 21, 2024
Start date
Apr 28, 2024 (estimated)
Primary completion
Jul 28, 2024 (estimated)
Completion
Dec 28, 2024 (estimated)
Last update
Mar 21, 2024

Study contacts

romain gillet, md
Contact
r.gillet@chru-nancy.fr
0033383851811
romain gillet
Contact
r.gillet@chru-nancy.fr
romain gillet, md
principal investigator · CHRU de Nancy

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Mar 2024. You cannot join it, but the record below documents what was studied.

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Other studies in this condition

Mucocele

Other studies from this sponsor

Central Hospital, Nancy, France

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