CClinicalTrials.gg
RecruitingNCT063100703DPPOAUpdated Jan 22, 2025

3D Printed Personalized Ostomy Appliance

An interventional study of 3D Printed Personalized Ostomy Appliance in 3D Printing, Ostomy and Leakage, sponsored by Carilion Clinic. Recruiting at 1 site in United States. Open to participants aged 18 Years to 100 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-01-22.

Sponsored by Carilion Clinic · Not applicable, Interventional, and Prevention

Phase
Not applicable
Study type
Interventional
Enrollment
30
Allocation
Not applicable
Ages
18 Years to 100 Years
Sex
All
01

Study summary

The goal of this clinical trial is to learn about the effectiveness of using a 3D scan for a personal ostomy appliance. The main question it aims to answer is:

  • Whether or not a 3D scan of a stoma reduces leakages and improves patient quality of life in regard to using a personalized ostomy appliance.

Participants will

  • Spend 2 weeks with their standard of care ostomy appliance
  • Spend 2 weeks with their personalized ostomy appliance made from a 3D scan
  • Participate in daily surveys and weekly quality of life surveys conducted over the phone
Read the detailed description

Formation of an ostomy is an operation that connects a hollow viscus, such as the bowel, to the skin. An ostomy appliance is worn to collect waste around the stoma, the externalized viscus organ. Ostomy appliances are emptied several times a day and are exchanged as infrequently as once per week or as frequently as multiple times per day. Unfortunately, half of all patients with an ostomy will suffer from complications such as peristomal skin breakdown, skin irritation, leaks, and bleeding. Stoma measuring guides are used to measure the ostomy appliance to achieve a well-fit skin barrier and prevent peristomal skin complications. Leaks both dramatically decrease patients' quality of life and result in skin irritation and other complications including infections.

Investigators propose utilizing advances in 3D scanning, computer-aided design (CAD) modeling, and 3D manufacturing to create a personalized ostomy appliance.

Site investigators will develop a 3D personalized ostomy appliance protocol featuring three phases: first, the patient's stoma is scanned using a 3D scanner in CRSudio2; second, the raw scan is edited using personalized variables to create a filtered mesh; third, the filtered mesh is printed to provide an ostomy template to the patient and currently available ostomy appliances are modified using a laser cutter to provide a personalized ostomy appliance to the patient. The selection of commercially available ostomy appliance will be done in coordination with the ostomy nursing team. Based upon the patient's body habitus and stoma, the ostomy nurse will select the recommended appliance that is available at Carilion Clinic. This will be the appliance that is customized using the laser cutter.

02

Conditions studied

  • 3D Printing
  • Ostomy
  • Leakage
03

Who can participate

Ages eligible
18 Years to 100 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • 18-100 years old
  • Must have had current ostomy appliance for > 6 weeks - if patients with stomas less than 6 weeks are included, their personalized templates will not be useful once the stoma size has changed after their initial scan.
  • Must have experienced > 1 leakage in the week leading up to day of consent. - If patients are not experiencing leakages, then there will be no baseline data to compare effectiveness of the post-3D appliance intervention.
  • Participants must be able to consent for themselves
  • Access to phone AND computer with internet access. Patient must be able to provide electronic mailing address for e-consent documentation and REDCap surveys.

Exclusion criteria

Exclusion Criteria:

  • Concern for patient being able to be reached over the phone or reliable internet access for REDCap survey completion
  • Existing peri-stomal skin breakdown including ulceration or mucocutaneous separation.
  • Diagnosis of infection around the peristomal region. (erythema is NOT an exclusion criteria)
04

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
30 participants (estimated)

Study arms

  • Experimental
    Receiving 3D Personalized Ostomy Appliance

    The personalized ostomy appliances are designed based off of a 3D scan. We will scan your ostomy to create a 3D picture in the computer system that is an exact copy of your ostomy using plastic. We then apply computer aided design (CAD) tools to modify your normal ostomy baseplates.

    Device: 3D Printed Personalized Ostomy Appliance

Interventions

  • Device3D Printed Personalized Ostomy Appliance

    Study procedures will include getting your stoma scanned, receiving personalized ostomy appliances in the mail, receiving a personalized ostomy template, which will be printed using a 3D printer, in the mail, and completing a daily symptom diary along with a weekly survey for 4 weeks.3D printing is done using a machine that takes the 3D image from the computer and prints a replica of the image using plastic or other materials.

05

What researchers measure

Primary outcomes

  1. Incidence of Leaks

    Number of leaks experienced on a daily basis by participant

    Time frame: 28 days

Secondary outcomes

  1. Number of appliances

    Number of ostomy bag changes completed by participant

    Time frame: 28 days

  2. Overall patient satisfaction

    Ostomy Leak Appliance Tool Survey will ask participants to answer questions related to their experiences of leaking within the previous 7 days, including information on the frequency of leakage and emotional impact of how a leak or risk of leakage affected how the participant felt. Participants will answer how they felt, whether they were able to complete usual day to day activities and how they coped by answering on a scale of "All of the time," "Often," "Sometimes," or "Rarely or never."

    Time frame: 28 days

06

Study locations

1 of 1 sites recruiting
07

Registry details

Key details

Study ID
NCT06310070
Lead sponsor
Carilion Clinic
Collaborators
Virginia Polytechnic Institute and State University
Responsible party
Sponsor
First posted
Mar 13, 2024
Start date
May 10, 2024
Primary completion
Mar 5, 2025 (estimated)
Completion
Jun 5, 2025 (estimated)
Last update
Jan 22, 2025

Study contacts

Adam Goode, MD
Contact
aegoode@carilionclinic.org
540-224-5170
Uma Kelavkar
Contact
ukelavkar@carilionclinic.org
Farrell Adkins, MD
principal investigator · Carilion Clinic

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
Yes
View the source record on ClinicalTrials.gov ↗

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