An interventional study of Caffeine-Based Energy Drink and Placebo in Substrate Oxidation, Energy Expenditure and Reaction Time, sponsored by Lindenwood University. Completed at 1 site in United States. Open to participants aged 18 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-10-17.
Sponsored by Lindenwood University · Not applicable, Interventional, and Other
The purpose of this study is to evaluate acute changes in rates of fat oxidation during exercise with and without the ingestion of a caffeine-based energy drink.
This study aims to investigate the impact of a caffeinated energy drink on cognitive function and exercise performance in healthy adults. The research will employ a randomized, double-blind, placebo-controlled, crossover design involving 15 participants. Initial screening includes health assessments and completion of a health history questionnaire, as well as a VO2peak assessment. Participants will replicate their diet before every study visit. Subsequent visits involve baseline assessments, ingestion of either a placebo or a caffeinated energy drink, followed by cognitive tests and a cycling exercise bout at moderate intensity, followed by a exercise performance cycling time trial. Measurements, including heart rate, perceived exertion, blood samples, and expired gases, will be collected during and after exercise. The study will have two identical testing visits, separated by at least a week, with participants consuming different beverages to assess their impact on cognitive function and exercise performance.
Lindenwood University is the lead sponsor of 29 studies on the registry; 6 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
12 oz Caffeine-based energy drink providing 200 mg caffeine
Dietary Supplement: Caffeine-Based Energy Drink
12 oz placebo void of all active ingredients
Other: Placebo
Energy drink with 200 mg caffeine
Placebo
Impact of a caffeine-based energy drink ingestion on fat oxidation rates during exercise.
Fat oxidation rate (grams/min) during exercise
Time frame: 150 minutes during exercise
Impact of a caffeine-based energy drink ingestion on energy expenditure rates during exercise.
Energy expenditure (kcals/min)
Time frame: 150 minutes during exercise
Impact of a caffeine-based energy drink ingestion on carbohydrate oxidation during exercise
Carbohydrate oxidation rates (grams/min)
Time frame: 150 minutes during exercise
Impact of a caffeine-based energy drink ingestion on plasma glycerol concentration
Plasma glycerol concentration
Time frame: 150 minutes after intervention ingestion
Impact of a caffeine-based energy drink ingestion on plasma free fatty acid concentration
Plasma free fatty acid concentration
Time frame: 150 minutes after intervention ingestion
Impact of a caffeine-based energy drink ingestion on ratings of perceived exertion
Rating of Perceived Exertion (RPE) scale
Time frame: 150 minutes after intervention ingestion
Impact of a caffeine-based energy drink ingestion on exercise performance
Cycling time trial
Time frame: 150 minutes after intervention ingestion
Impact of a caffeine-based energy drink ingestion on reaction time
Simple/ choice reaction time
Time frame: 150 minutes after intervention ingestion
Impact of a caffeine-based energy drink ingestion on trail making test performance
Trail making test
Time frame: 150 minutes after intervention ingestion
Impact of a caffeine-based energy drink ingestion on Cognition
Serial 7 Cognitive processing test
Time frame: 150 minutes after intervention ingestion
Impact of a caffeine-based energy drink ingestion on adverse events
Self-reported adverse events
Time frame: 3 weeks
Impact of a caffeine-based energy drink ingestion on heart rate
Heart rate (bpm)
Time frame: 3 weeks
Impact of a caffeine-based energy drink ingestion on blood pressure
Blood Pressure (mmHg)
Time frame: 3 weeks
Plan to share: No — Investigators do not plan to make individual participant data available to other researchers
No publications or documents are linked to this record.
This study is completed, as verified in Oct 2024. You cannot join it, but the record below documents what was studied.
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Lindenwood University