An observational study in Cancer and Metastatic Cancer, sponsored by UNC Lineberger Comprehensive Cancer Center. Recruiting at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-05-06.
Sponsored by UNC Lineberger Comprehensive Cancer Center · Observational
The purpose of this registry is to collect clinical data from participants attending UNC Hospitals who present with metastatic cancer and are evaluated to receive radiation therapy as part of their standard of care treatment. The goal of this study is to provide a foundation for studies designed to identify projects across the translational continuum related to metastatic cancer and radiation therapy treatment. The relevant clinical data will be linked to patient-reported outcomes (PROs) thus allowing for a unique and robust dataset. Ultimately, this registry will provide current and future studies with the ability to analyze the correlation of radiation therapy regimens with metastatic cancer outcomes.
9,365 studies on the registry are indexed under Neoplasms; 2,489 are open to participants now.
This study's planned enrollment of 2,000 is above the median of 204 across 1,683 observational studies indexed under Neoplasms.
Browse Neoplasms studies →UNC Lineberger Comprehensive Cancer Center is the lead sponsor of 414 studies on the registry; 96 are open to participants now.
Of its 32 completed or terminated interventional studies of FDA-regulated products, 25 (78%) have results posted.
Counted across the registry records on this site, refreshed daily.
Subjects with metastatic cancer receiving palliative radiation therapy at the University of North Carolina Chapel Hill.
Written informed consent was obtained to participate in the study and HIPAA
Authorization for release of personal health information. Ability to understand and willingness to sign informed consent
Diagnosed with or is suspected to have metastatic cancer.
Age ≥ 18 years at the time of consent.
Evaluated to receive radiation therapy as part of their standard-of-care treatment plan.
Exclusion Criteria:
All participants must not meet any of the following exclusion criteria prior to enrollment to participate in this study:
Any serious medical or psychiatric disorder that would interfere with the participant's ability to give informed consent.
Subjects who are with metastatic cancer receive palliative radiation therapy.
Radiation: Radiation therapy
Subjects with metastatic cancer receive radiation therapy.
Clinical Data
Clinical data and radiological assessments from participants with metastatic cancer receiving radiation therapy as a part of the standard of care will be collected.
Time frame: Up to 1 month
Patient reported outcomes (PRO)
Patient reported outcomes (PRO) from participants will be collected at different time points.
Time frame: Baseline, 1 month, 3 months, 6 months, 9 months, and 12 months
Plan to share: No
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
Contact study teamGet an email when the registry record changes — status, dates, results — or when someone posts here.
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UNC Lineberger Comprehensive Cancer Center