An observational study in Idiopathic Inflammatory Myopathies, sponsored by RenJi Hospital. Not yet recruiting. Open to participants aged 18 Years to 75 Years. Per ClinicalTrials.gov, last updated 2024-03-12.
Sponsored by RenJi Hospital · Observational
Idiopathic inflammatory myositis (IIM), also known as myositis, are a heterogeneous group of diseases characterized by chronic inflammation of striated muscles and skin, with different clinical manifestations, treatment responses, and prognosis. This project will build a clinical follow-up cohort for idiopathic inflammatory myositis (IIM) centered on Renji Hospital, Shanghai Jiao Tong University School of Medicine, to promote the clinical and pathogenesis of this group of diseases.
242 studies on the registry are indexed under Myositis; 103 are open to participants now.
This study's planned enrollment of 1,000 is above the median of 226 across 72 observational studies indexed under Myositis.
Browse Myositis studies →RenJi Hospital is the lead sponsor of 535 studies on the registry; 244 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Aged 18-75 years and eligible for the 2017 European League Against Rheumatism/American College of Rheumatology.
Inclusion Criteria:Subjects must meet the following criteria for inclusion in this study: meet the 2017 EULAR/ACR classification criteria for inflammatory myopathy (IIM) or the 2018 ENMC-DM classification criteria (see above), plus:
Cooperate with follow-up, examination and treatment and voluntarily sign the informed consent form.
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Exclusion Criteria:Potential subjects who meet the inclusion criteria will be excluded if they meet any of the following criteria:
a. IIM with other connective tissue diseases; b. Negative myositis antibody test; c. Those who are in the period of acute infection, or have a history of active tuberculosis in the past; d. People with allergies or allergies to multiple drugs; e. Those who have mental illness or other reasons and cannot cooperate with examination, follow-up or treatment; f. Women who are pregnant, or are trying to become pregnant; g. Those who are participating in or have participated in clinical trials within the specified time.
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Patients with IMM will be grouped according to the type of positive myositis-specifc autoantibody,and then again according to whether and what type of tumor they had comorbid.
Other: no interventions were involved
Patients with IMM will be grouped according to the type of positive myositis-specifc autoantibody,and then again according to whether and what type of tumor they had comorbid.
Other: no interventions were involved
no interventions were involved
High Resolution Computed Tomography of Chest
High Resolution Computed Tomography of Chest will be used to assess the incidence of interstitial pneumonia.
Time frame: three months
Cutaneous Disease Area and Severity Index
Cutaneous Disease Area and Severity Index will be used to assess the the severity of the rash.
Time frame: three months
Forced vital capacity
t refers to the maximum amount of air that cr trying to inhale as quickly as possible.
Time frame: three months
Manual Muscle Testing
Manual Muscle Testing will be used to assess patients with muscle weakness.
Time frame: three months
Forced expiratory volume in one second
It refers to the volume of the maximum exhalation exhaled in the first second of the maximum deep inhalation.
Time frame: three months
Serum creatine kinase
Serum creatine kinase will be used to assess the disease activity in idiopathic inflammatory myopathies.
Time frame: three months
No study locations are listed for this record.
This study is not yet recruiting, as verified in Feb 2024. You cannot join it, but the record below documents what was studied.
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RenJi Hospital