An interventional study of Total intravenous anesthesia with Byfavo and Inhalation anesthesia with Sevoflurane in Thyroid Neoplasm and Cough, sponsored by Yonsei University. Completed at 1 site in Korea, Republic of. Open to participants aged 19 Years and older. Per ClinicalTrials.gov, last updated 2024-02-23.
Sponsored by Yonsei University · Not applicable, Interventional, and Prevention
This study is a randomized controlled trial. Adult patients undergoing thyroidectomy under general anesthesia at Severance Hospital and Yonsei Cancer Center are included in tis study. For intervention group, patients receive anesthesia with total intravenous remimazolam, while for control group, patients receive anesthesia with inhalation anesthetic.
The primary end point of the study is to determine whether coughing during endotracheal tube extubation is less when anesthesia is maintained with intravenous remimazolam compared to inhalation anesthetics. The secondary end points are cough score (graded into 4 levels), frequency of reoperation due to postoperative bleeding, These include the frequency of hypertension during the extubation process and whether additional painkillers are used in the recovery room.
802 studies on the registry are indexed under Thyroid Neoplasms; 216 are open to participants now.
This study's enrollment of 106 is above the median of 51 across 507 interventional studies indexed under Thyroid Neoplasms.
Browse Thyroid Neoplasms studies →Yonsei University is the lead sponsor of 1,387 studies on the registry; 232 are open to participants now.
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Adult patients aged 19 years or older undergoing thyroidectomy under general anesthesia at Severance Hospital Cancer Center.
Exclusion Criteria:
General anesthesia is maintained with intravenous administration of Byfavo.
Drug: Total intravenous anesthesia with Byfavo
Drug: Inhalation anesthesia with Sevoflurane
General anesthesia is maintained with intravenous continuous administration of Byfavo.
General anesthesia is maintained with Sevoflurane.
Proportion of patients not coughing during postoperative extubation
Proportion of patients not coughing during postoperative extubation
Time frame: Until discharge (3days on average)
Cough score
Cough score (4 scale score: 1- no cough, 2: cough once, 3: cough lating less than 5 seconds, 4: cough lating longer than 5 seconds.)
Time frame: Until discharge (3days on average)
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Feb 2024. You cannot join it, but the record below documents what was studied.
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Yonsei University