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CompletedNCT06240845Updated Feb 5, 2024

Effect of High Versus Low-level Laser Therapy in Patients of Lumber Radiculopathy

An interventional study of High-level laser therapy and Low-level laser therapy in Lumbar Radiculopathy, sponsored by Riphah International University. Completed at 2 sites in Pakistan. Open to participants aged 40 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-02-05.

Sponsored by Riphah International University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 5 months after the study started (first participant enrolled Aug 2023, registered Jan 2024).
Phase
Not applicable
Study type
Interventional
Enrollment
38
Allocation
Randomized
Ages
40 Years to 65 Years
Sex
All
01

Study summary

To Compare the effects of high-level laser therapy (HLLT) and low-level laser therapy (LLLT) on pain in patients with lumbar radiculopathy.

02

Conditions studied

  • Lumbar Radiculopathy

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Keywords

  • HLLT, Laser therapy , LLLT, Lumber radiculopathy, Sciatica
03

In context

Radiculopathy

488 studies on the registry are indexed under Radiculopathy; 141 are open to participants now.

This study's enrollment of 38 is below the median of 60 across 376 interventional studies indexed under Radiculopathy.

Browse Radiculopathy studies →

Lead sponsor

Riphah International University is the lead sponsor of 2,133 studies on the registry; 633 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
40 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Patients of both genders male and female will be included.
  • Patients aged 40-65 years will be included.
  • Patients with a diagnosis of lumbar radiculopathy confirmed by clinical evaluation by a physician or physiotherapist.
  • Patients with a history of radicular leg pain and/or numbness or tingling sensation in the leg.
  • a positive score on the Straight Leg Raise (pain between 35 degrees and 75 degrees), pain limiting functional ability, and scores at least 3/10 on the VAS, restricted lumbar range of motion - 25% flexion, 20% extension.
  • Patients who have not received any form of treatment for lumbar radiculopathy within the past 3 months

Exclusion criteria

Exclusion Criteria:

  • Patients with a history of spinal surgery in the last 2 years or spinal deformity.
  • Patients with a history of fracture or dislocation of the lumbar spine.
  • Patients with a diagnosis of any other neurological disorder or neuropathy.
  • Patients who are pregnant or breastfeeding.
  • Patients with any other medical condition that may interfere i.e. inflammatory rheumatic disease, cardiac pacemaker, continuing that may interfere with the study outcomes or put them at risk with the study outcomes or put them at risk.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Investigator)
Enrollment
38 participants (actual)

Study arms

  • Experimental
    High Level Laser Therapy

    This group received High-level laser therapy along with conventional physiotherapy treatment 3 times per week for 6 weeks.

    Other: High-level laser therapy

  • Experimental
    Low Level Laser Therapy

    This group received Low-level laser therapy along with conventional physiotherapy treatment 3 times per week for 6 weeks.

    Other: Low-level laser therapy

Interventions

  • OtherHigh-level laser therapy

    This group received High-level laser therapy along with conventional physiotherapy treatment 3 times per week for 6 weeks.

  • OtherLow-level laser therapy

    This group received Low-level laser therapy along with conventional physiotherapy treatment 3 times per week for 6 weeks.

06

What researchers measure

Primary outcomes

  1. Pain Level

    Visual Analogue scale

    Time frame: 6 weeks

  2. Rang of motion

    Straight Leg Raise

    Time frame: 6 weeks

  3. Level of Disability

    Oswestry Disability Index (ODI)

    Time frame: 6 weeks

  4. To measure Quality of Life

    Health Questionnaire (EQ-5D-5L)

    Time frame: 6 weeks

07

Study locations

2 sites
  • Faiq Medical Complex
    Faisalābad, Punjab 54000, Pakistan
  • Independent University Hospital
    Faisalābad, Punjab 54000, Pakistan
08

References and documents

Publications

  • Kolu E, Buyukavci R, Akturk S, Eren F, Ersoy Y. Comparison of high-intensity laser therapy and combination of transcutaneous nerve stimulation and ultrasound treatment in patients with chronic lumbar radiculopathy: A randomized single-blind study. Pak J Med Sci. 2018 May-Jun;34(3):530-534. doi: 10.12669/pjms.343.14345. PubMed 30034410 ↗
  • Ince S, Eyvaz N, Dundar U, Toktas H, Yesil H, Eroglu S, Adar S. Clinical Efficiency of High-Intensity Laser Therapy in Patients With Cervical Radiculopathy: A 12-Week Follow-up, Randomized, Placebo-Controlled Trial. Am J Phys Med Rehabil. 2024 Jan 1;103(1):3-12. doi: 10.1097/PHM.0000000000002275. Epub 2023 May 1. PubMed 37204965 ↗
  • Konstantinovic LM, Cutovic MR, Milovanovic AN, Jovic SJ, Dragin AS, Letic MDj, Miler VM. Low-level laser therapy for acute neck pain with radiculopathy: a double-blind placebo-controlled randomized study. Pain Med. 2010 Aug;11(8):1169-78. doi: 10.1111/j.1526-4637.2010.00907.x. PubMed 20704667 ↗
  • Ahmed I, Bandpei MAM, Gilani SA, Ahmad A, Zaidi F. Effectiveness of Low-Level Laser Therapy in Patients with Discogenic Lumbar Radiculopathy: A Double-Blind Randomized Controlled Trial. J Healthc Eng. 2022 Feb 27;2022:6437523. doi: 10.1155/2022/6437523. eCollection 2022. PubMed 35265302 ↗
  • Ahmed I, Mohseni Bandpei MA, Gilani SA, Ahmad A, Zaidi F. Correlation Analysis Between Pain Intensity, Functional Disability and Range of Motion Using Low-Level Laser Therapy in Patients With Discogenic Lumbar Radiculopathy: A Cross-sectional Study. J Lasers Med Sci. 2022 Jun 6;13:e26. doi: 10.34172/jlms.2022.26. eCollection 2022. PubMed 36743144 ↗
  • Danazumi MS, Bello B, Yakasai AM, Kaka B. Two manual therapy techniques for management of lumbar radiculopathy: a randomized clinical trial. J Osteopath Med. 2021 Feb 26;121(4):391-400. doi: 10.1515/jom-2020-0261. PubMed 33705612 ↗
  • Rogerson A, Aidlen J, Jenis LG. Persistent radiculopathy after surgical treatment for lumbar disc herniation: causes and treatment options. Int Orthop. 2019 Apr;43(4):969-973. doi: 10.1007/s00264-018-4246-7. Epub 2018 Nov 29. PubMed 30498910 ↗
  • Kostadinovic S, Milovanovic N, Jovanovic J, Tomasevic-Todorovic S. Efficacy of the lumbar stabilization and thoracic mobilization exercise program on pain intensity and functional disability reduction in chronic low back pain patients with lumbar radiculopathy: A randomized controlled trial. J Back Musculoskelet Rehabil. 2020;33(6):897-907. doi: 10.3233/BMR-201843. PubMed 32675390 ↗
  • Ghasabmahaleh SH, Rezasoltani Z, Dadarkhah A, Hamidipanah S, Mofrad RK, Najafi S. Spinal Manipulation for Subacute and Chronic Lumbar Radiculopathy: A Randomized Controlled Trial. Am J Med. 2021 Jan;134(1):135-141. doi: 10.1016/j.amjmed.2020.08.005. Epub 2020 Sep 13. PubMed 32931763 ↗

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 5, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06240845
Lead sponsor
Riphah International University
Responsible party
Sponsor
First posted
Feb 5, 2024
Start date
Aug 1, 2023
Primary completion
Sep 30, 2023
Completion
Oct 10, 2023
Last update
Feb 5, 2024

Study contacts

Binash Afzal, PHD*
principal investigator · Riphah international university lahore campus

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Jan 2024. You cannot join it, but the record below documents what was studied.

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