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CompletedNCT06239948Updated Dec 23, 2025

The Brain Symphony For Post-Stroke Rehabilitation

An interventional study of With Music and Without Music in Stroke, sponsored by University of Malaya. Completed at 1 site in Malaysia. Open to participants aged 55 Years to 80 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-12-23.

Sponsored by University of Malaya · Not applicable, Interventional, and Supportive care

From the registry’s dates

  • Registered 6 years after the study started (first participant enrolled Jan 2018, registered Jan 2024).
Phase
Not applicable
Study type
Interventional
Enrollment
40
Allocation
Randomized
Ages
55 Years to 80 Years
Sex
All
01

Study summary

Music listening intervention has made great strides in improving the condition of stroke survivors. Thus, this research explores the effects of music listening intervention on post-stroke survivors during rehabilitation by using P. Ramlee songs.

Read the detailed description

Objective: Music listening intervention has made great strides in improving the condition of stroke survivors. Thus, this research explores the effects of music listening intervention on post-stroke survivors during rehabilitation by using P. Ramlee songs.

Materials \& Methods: In the first phase, surveys were conducted to determine the selection of songs to be used in the second phase. The second phase is applying music listening intervention on a small sample of 20 subjects, aged 55 years old and above. The participants were categorized into two groups: stroke survivors and healthy individuals and randomized into control group (without music) and experimental group (with music). The second phase consists of three stages. Stage one is to pre-screen and select potential subjects before the experiment. The second stage aims to determine the effect of P. Ramlee music on stroke survivors during their rehabilitation through augmenting their brain neuroplasticity with measurement of the MEP using TMS. The final stage compares the effects of MEP between lesion and non-lesion areas.

02

Conditions studied

  • Stroke

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Keywords

  • Music Listening
  • Stroke
  • Rehabilitation
  • Transcranial Magnetic Stimulation (TMS)
  • Neuroplasticity
  • P. Ramlee Music
03

In context

Stroke

7,286 studies on the registry are indexed under Stroke; 2,007 are open to participants now.

This study's enrollment of 40 is below the median of 50 across 5,369 interventional studies indexed under Stroke.

Browse Stroke studies →

Lead sponsor

University of Malaya is the lead sponsor of 280 studies on the registry; 55 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
55 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Healthy
  • No history of seizures or epilepsy
  • Able to hear well
  • Able to attend experiment sessions without scheduling conflicts
  • No contraindications to undergoing TMS

Exclusion criteria

Exclusion Criteria:

  • None
05

Study design

Phase
Not applicable
Primary purpose
Supportive care
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Triple (Participant, Investigator, Outcomes assessor)
Enrollment
40 participants (actual)

Study arms

  • Placebo comparator
    control group

    without music

    Other: Without Music

  • Experimental
    experimental group

    with music

    Other: With Music

Interventions

  • OtherWith Music

    each subject was placed in a TMS laboratory with music for 20 minutes

  • OtherWithout Music

    each subject was placed in a TMS laboratory without music for 20 minutes

06

What researchers measure

Primary outcomes

  1. Transcranial Magnetic Stimulation (TMS)

    Wilcoxon signed-ranks test for the comparison of pre- and post- experiment

    Time frame: 24 months

07

Study locations

1 site
  • Universiti Malaya Medical Centre
    Kuala Lumpur, Kuala Lumpur 50603, Malaysia
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 23, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06239948
Lead sponsor
University of Malaya
Responsible party
Sponsor
First posted
Feb 2, 2024
Start date
Jan 1, 2018
Primary completion
Dec 31, 2020
Completion
Dec 31, 2020
Last update
Dec 23, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jan 2024. You cannot join it, but the record below documents what was studied.

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