An interventional study of Collagen and Placebo in Osteo Arthritis Knee, sponsored by Prince of Songkla University. Completed at 1 site in Thailand. Open to participants aged 50 Years to 80 Years. Per ClinicalTrials.gov, last updated 2024-12-24.
Sponsored by Prince of Songkla University · Not applicable, Interventional, and Treatment
Randomized controlled trial
Targeted patients who come to receive treatment for osteoarthritis that meets the research indications will be assigned to a random group by the box of 4 randomization method, with a sequence that is randomly generated by a computer. The groups are divided into two groups:
Group 1: Patients who have taken 480 mg of hydrolyzed collagen and 20 mg of undenatured type II collagen
Group 2: Control patients will take placebo
Primary outcome : Pain level
4,445 studies on the registry are indexed under Osteoarthritis; 582 are open to participants now.
This study's enrollment of 68 is close to the median of 70 across 3,474 interventional studies indexed under Osteoarthritis.
Browse Osteoarthritis studies →Prince of Songkla University is the lead sponsor of 116 studies on the registry; 13 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Patients who have taken 480 mg of hydrolyzed collagen and 20 mg of undenatured type II collagen (in one tablet) 2 tabs a day
Dietary Supplement: Collagen
Control patients will take placebo 2 tabs a day
Other: Placebo
Patients who have taken 480 mg of hydrolyzed collagen and 20 mg of undenatured type II collagen (in one tablet) 2 tabs a day
Control patients will take placebo 2 tabs a day.
Pain (VNRS)
Pain level (verbal numerical rating scale :VNRS) - 0 is no pain and 10 is the worst pain
Time frame: 12 weeks
Knee and Osteoarthritis Outcome Score (KOOS)
Knee and Osteoarthritis Outcome Score (KOOS) - 100 indicates the best possible results and 0 the worst outcome
Time frame: 12 weeks
Rescue medication
Amount of pain medication intake
Time frame: 12 weeks
Patient satisfaction
Patient satisfaction (verbal numerical rating scale :VNRS) - (0-10; 0=worst and 10=best)
Time frame: 12 weeks
Plan to share: Yes
Supporting information: Study protocol, Clinical study report
Time frame: Data will become available and for 1 year after publication.
Access criteria: Open Science Framework (OSF)
Data sharing details ↗ · osf.io
Ran from Nov 2023 to primary completion in Aug 2024, 9 months.
Of 1,126 non-industry interventional studies with no phase under Osteoarthritis, half reached primary completion within 18 months of starting (the median), counting those still running; a quarter within 8 and three quarters within 38. This study's 9 months is below that.
Counting every sponsor, half of 1,315 studies reached it within 19 months; a quarter within 8 and three quarters within 39.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Dec 2024. You cannot join it, but the record below documents what was studied.
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Studies of the drug tested here: Collagen
Prince of Songkla University →