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CompletedNCT06228911Updated Jan 30, 2024

Increased Blood Glucose Levels After Steroid Injection

An interventional study of steroid (triamcinolone) in Osteoarthritis, Knee and Diabete Type 2, sponsored by Syrian Private University. Completed at 1 site in Syrian Arab Republic. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2024-01-30.

Sponsored by Syrian Private University · Not applicable, Interventional, and Screening

From the registry’s dates

  • Registered 4 years after the study started (first participant enrolled Jan 2020, registered Jan 2024).
Phase
Not applicable
Study type
Interventional
Enrollment
600
Allocation
Non-randomized
Ages
18 Years and older
Sex
All
01

Study summary

a sample of 600 patients diagnosed as Knee osteoarthritis injected with 40 mg triamcinolone, recorded their morning fasting blood glucose levels for 7 days before injection used as the baseline blood glucose level, which was compared with FBS levels for 14 days after steroid injection. Our study compared the differences in blood glucose changes between HbA1c >7% and HbA1c ≤7% groups and those between insulin and non-insulin treated groups.

02

Conditions studied

  • Osteoarthritis, Knee
  • Diabete Type 2
03

In context

Osteoarthritis, Knee

3,302 studies on the registry are indexed under Osteoarthritis, Knee; 608 are open to participants now.

This study's enrollment of 600 is above the median of 70 across 2,731 interventional studies indexed under Osteoarthritis, Knee.

Browse Osteoarthritis, Knee studies →

Lead sponsor

Syrian Private University is the lead sponsor of 8 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

Age > 18 years, patients with knee osteoarthritis diagnosed according to American College of Rheumatology (ACR) Criteria (17), and grade1-3 in Kallgren-Laurence radiographic scale (18), whom failed to response to medical treatment including paracetamol and nonsteroidal anti-inflammatory medication, and to physical therapy, checking their blood glucose values daily.

Exclusion criteria

Exclusion Criteria:

Patients who were unable to provide consent, patients had any contraindications to corticosteroids, patients who had received oral corticosteroid in the past 6 months or corticosteroid injection in the previous 3 months, patients who had no monitoring HbA1c level before injection or also whom had not monitor blood glucose levels before or after injection.

05

Study design

Phase
Not applicable
Primary purpose
Screening
Allocation
Non-randomized
Intervention model
Factorial assignment
Masking
None (open label)
Enrollment
600 participants (actual)

Study arms

  • Experimental
    insulin treated group

    Drug: steroid (triamcinolone)

  • Experimental
    non-insulin treated groups

    Drug: steroid (triamcinolone)

Interventions

  • Drugsteroid (triamcinolone)

    triamcinolone is a synthetic corticosteroid medication used topically to treat various skin conditions, to relieve the discomfort of mouth sores, and by injection into joints to treat various joint conditions

06

What researchers measure

Primary outcomes

  1. high blood glucose

    glucose increases after steroid dose

    Time frame: 3 years

  2. low blood glucose

    glucose decreases after steroid dose

    Time frame: 3 years

07

Study locations

1 site
  • Faculty of Medicine, Damascus University, Syria
    Damascus, 1, Syrian Arab Republic
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 30, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT06228911
Lead sponsor
Syrian Private University
Responsible party
Diaa Haj Ali (Medical Doctor Diaa Haj Ali, Syrian Private University) — Principal investigator
First posted
Jan 29, 2024
Start date
Jan 15, 2020
Primary completion
Sep 15, 2023
Completion
Sep 15, 2023
Last update
Jan 30, 2024

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jan 2024. You cannot join it, but the record below documents what was studied.

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