An interventional study of Smoking Cessation Intervention and Saliva Collection in Smoking Cessation, Cigarette Smoking-Related Carcinoma and Lung Carcinoma, sponsored by University of California, San Francisco. Active, not recruiting at 1 site in United States. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-10-05.
Sponsored by University of California, San Francisco · Not applicable, Interventional, and Prevention
This study evaluates a smoking cessation intervention (CONNECTing to LungCare) for improving shared decision-making conversations about smoking cessation and lung cancer screening between patients and providers. Shared decision making is a patient care model in which providers offer information regarding risks and benefits, patients express their values and preferences, and then healthcare decisions are jointly discussed between the patient and provider. Patient education, aided by decision support tools, can increase patients' knowledge, decrease their decisional conflict, promote decision making, and improve the patients' perception of risk. CONNECTing to LungCare is an interactive education intervention that addresses lung cancer screening and smoking cessation and provides participants with a tailored summary that may make them more likely to have shared decision-making discussions with their providers about smoking cessation and lung cancer screening.
PRIMARY OBJECTIVES:
Aim 1: Development of the smoking cessation and LCS intervention, CONNECTing to LungCare.
Aim 2: Test CONNECTing to Lung Care for Feasibility and Acceptability (N=120)
Aim 3: To qualitatively evaluate feasibility and acceptability of the intervention and study procedures from the perspectives of patients, providers, staff and administrators and other stakeholders.
OUTLINE:
BETA TESTING: Participants interact with the CONNECTing to LungCare intervention and provide feedback in support of intervention refinement.
FEASIBILITY TRIAL: Participants are randomized to 1 of 2 groups.
GROUP I: Participants receive the CONNECTing to LungCare intervention, including education about the benefits and risks of LCS and the importance of shared decision making, computerized assessments of the participant's smoking status, readiness to quit and concerns about quitting, and video segments tailored to the participant's responses to assessment questions, prior to their primary care appointment. Participants and their providers receive a tailored summary of the participant's concerns and barriers to quitting to enhance motivation for smoking cessation and shared decision making discussions. Participants then receive up to 3 follow-up phone calls over 10-15 minutes each encouraging them to follow up with their provider, to complete the shared decision-making conversation, obtain LCS if appropriate, and access smoking cessation resources. Participants may also receive brief, tailored follow-up text messages that include links to video segments or cessation resources 1-3 times weekly.
GROUP II: Participants receive usual care from their provider at their primary care appointment.
After completion of study intervention, participants are followed up at 1 and 3 months.
304 studies on the registry are indexed under Smoking Cessation; 139 are open to participants now.
This study's enrollment of 53 is below the median of 153 across 285 interventional studies indexed under Smoking Cessation.
Browse Smoking Cessation studies →University of California, San Francisco is the lead sponsor of 2,132 studies on the registry; 375 are open to participants now.
Of its 262 completed or terminated interventional studies of FDA-regulated products, 196 (75%) have results posted.
Counted across the registry records on this site, refreshed daily.
Key Informant Interviews:
- Must be working in one of the clinics participating in CONNECTing to LungCare.
Exclusion Criteria:
Participants interact with the CONNECTing to LungCare intervention and provide feedback in support of intervention refinement.
Behavioral: Smoking Cessation Intervention · Other: Survey Administration
Participants receive the CONNECTing to LungCare intervention, including education about the benefits and risks of LCS and the importance of shared decision making, computerized assessments of the participant's smoking status, readiness to quit and concerns about quitting, and video segments tailored to the participant's responses to assessment questions, prior to their primary care appointment. Participants and their providers receive a tailored summary of the participant's concerns and barriers to quitting to enhance motivation for smoking cessation and shared decision-making discussions. Participants then receive up to 3 follow-up phone calls over 10-15 minutes each encouraging them to follow up with their provider, to complete the shared decision-making conversation, obtain LCS if appropriate, and access smoking cessation resources. Participants may also receive brief, tailored follow-up text messages that include links to video segments or cessation resources 1-3 times weekly.
Behavioral: Smoking Cessation Intervention · Other: Saliva Collection · Other: Survey Administration
Participants receive usual care from their provider at their primary care appointment.
Behavioral: Smoking Cessation Intervention · Other: Saliva Collection · Other: Survey Administration
Multimedia program administered either remotely or in person
Also known as: CONNECTing to LungCare intervention
Saliva samples will be collected from each participant
Also known as: Biospecimen Collection, Specimen Sample, Saliva Sample
Ancillary studies
Recruitment rate
The percentage of participants who were contacted and joined the study will be reported.
Time frame: Up to 1 year
Retention rates
The percentage of participants who joined the study and completed the program will be reported.
Time frame: Up to 1 year
Adherence rates
The percentage of participants who joined the study and completed all tasks within the program will be reported.
Time frame: Up to 1 year
Overall time required to recruit to the target sample size (Feasibility Cohort)
The overall time in weeks required to recruit participants for the feasibility cohort will be reported.
Time frame: Up to 1 year
Number of eligible participants
The number of eligible participants required to recruit the required sample size will be reported
Time frame: Up to 1 year
Smoking cessation rates
Will evaluate the impact of the intervention on smoking cessation rates. Rates of smoking cessation will be measured by self-report and validated by salivary cotinine levels.
Time frame: At 3 months
Lung cancer screening (LCS) rates
Rates of LCS will be evaluated through review of the electronic health record (EHR)
Time frame: Up to 3 months
Shared decision making about LCS
Evidence of shared decision-making conversation will be obtained through one week follow up phone call and with review of the EHR three months after the primary care physician visit.
Time frame: Up to 3 months
Plan to share: No
No publications or documents are linked to this record.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is active, not recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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University of California, San Francisco