An interventional study of Surgical excision in Localized Gingival Enlargement, Epulides and Recurrence, sponsored by Semmelweis University. Recruiting at 1 site in Hungary. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-04-04.
Sponsored by Semmelweis University · Not applicable, Interventional, and Treatment
Non-inflammatory recessions and Miller class I-II-III. mucogingival defects after elimination of localized gingival enlargements are frequently encountered challenges in the daily practice. In Miller class II-III. recessions the lack of keratinized tissues often compromise the maintenance a proper oral hygiene, this can cause inflammation, which can result in further periodontal attachment loss. In the literature there are some approaches that aim at widening of keratinized tissues and root coverage at the same time, such as the subperiosteal envelope technique (SET) (Allen 1994) combined with a subepithelial connective tissue graft (SCTG) or a partially epithelialized connective tissue graft (PE-SCTG) (Stimmelmayr 2011). In the eradication of localized gingival enlargement postoperative complications following surgical removal, such as recurrence and subsequent gingival recessions as well as loss of keratinized tissues are commonly observed. Nevertheless, a state of the art comprehensive treatment approach has not been reported yet to overcome the above mentioned sequels. The aim of this study is to present a periodontal plastic surgical approach to definitively eliminate localized gingiva enlargements and to simultaneously correct consecutive Miller class I II-III. recessions, esthetic disturbances. (Ethical committee permission number: SE RKEB: 185/2020.)
88 studies on the registry are indexed under Gingival Diseases; 23 are open to participants now.
This study's planned enrollment of 22 is below the median of 46 across 69 interventional studies indexed under Gingival Diseases.
Browse Gingival Diseases studies →Semmelweis University is the lead sponsor of 140 studies on the registry; 56 are open to participants now.
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Exclusion Criteria:
Surgical excision and periodontal reconstruction according to the remaining amount of keratinized gingiva
Procedure: Surgical excision
Periodontal plastic reconstruction of the subsequent soft tissue dehiscence after the surgical excision of the localized gingival enlargement
Also known as: periodontal plastic reconstruction
Recurrence
If there is recurrence after the proper elimination of the enlargement and the one-staged reconstruction
Time frame: 3 months, 6 months
Keratinized Gingiva Height
The height of the remaining keratinized gingiva
Time frame: 1 month, 3 months, 6 months
Gingival Recession
The subsequent gingiva recession that remains after the elimination of the enlargement and the reconstruction of the soft tissue
Time frame: 1 month, 3 months, 6 months
Plan to share: No
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