An interventional study of Mouth cancer warning and Throat cancer warning in Alcohol Drinking, sponsored by Stanford University. Completed at 1 site in United States. Open to participants aged 21 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-02-13.
Sponsored by Stanford University · Not applicable, Interventional, and Prevention
The primary objective is to evaluate whether alcohol warnings about different topics elicit higher perceived message effectiveness than control messages. The secondary objective is to evaluate whether alcohol warnings about different topics elicit higher reactance than control messages.
Participants will complete a within-subjects online randomized experiment in which they will view and rate messages on the risk of alcohol consumption. Participants will view and rate 12 messages total: 10 warning messages and 2 control messages. They will rate each message on perceived message effectiveness (primary outcome) and message reactance (secondary outcome). The 10 warning messages will be about 5 different warning topics (i.e., 2 messages per topic) and the 2 control messages will be about 1 control topic (2 messages per topic). In this within-subjects experiment, the survey will present the topics in random order and the messages within each topic in random order.
925 studies on the registry are indexed under Alcohol Drinking; 172 are open to participants now.
This study's enrollment of 2,522 is above the median of 108 across 802 interventional studies indexed under Alcohol Drinking.
Browse Alcohol Drinking studies →Stanford University is the lead sponsor of 2,117 studies on the registry; 425 are open to participants now.
Of its 259 completed or terminated interventional studies of FDA-regulated products, 197 (76%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Participants view 12 messages: 10 messages related to health topics (2 messages for each of 5 randomly selected health topics from among all health topics) and 2 control messages.
Behavioral: Mouth cancer warning · Behavioral: Throat cancer warning · Behavioral: Voice box (larynx) warning · Behavioral: Esophagus cancer warning · Behavioral: Liver cancer warning · Behavioral: Colon and rectum cancer warning · Behavioral: Breast cancer · Behavioral: Cancer (generic, not site-specific) · Behavioral: Addiction and neurological changes · Behavioral: Hypertension · Behavioral: Liver damage · Behavioral: Harm to fetus · Behavioral: Dementia · Behavioral: Impaired sleep · Behavioral: Drinking guidelines · Behavioral: Control · Behavioral: Road injuries
Participants will view messages about the risk of mouth cancer from alcohol consumption.
Participants will view messages about the risk of throat cancer from alcohol consumption.
Participants will view messages about the risk of voice box (larynx) cancer from alcohol consumption.
Participants will view messages about the risk of esophagus cancer from alcohol consumption.
Participants will view messages about the risk of liver cancer from alcohol consumption.
Participants will view messages about the risk of colon and rectum cancer from alcohol consumption.
Participants will view messages about the risk of breast cancer from alcohol consumption.
Participants will view messages about the risk of cancer (not site-specific) from alcohol consumption.
Participants will view messages about the risk of addiction and neurological changes from alcohol consumption.
Participants will view messages about the risk of hypertension from alcohol consumption.
Participants will view messages about the risk of liver damage from alcohol consumption.
Participants will view messages about the risk of harm to a fetus from alcohol consumption during pregnancy.
Participants will view messages about the risk of dementia from alcohol consumption.
Participants will view messages about the risk of impaired sleep from alcohol consumption.
Participants will view messages about guidelines for alcohol consumption.
Participants will view neutral messages unrelated to the harms of alcohol consumption.
Participants will view messages about the risk of road injuries from alcohol consumption.
Perceived message effectiveness
The study will assess perceived message effectiveness using 1 item: "How much does this message discourage you from wanting to drink alcohol?" Response options will range from "not at all" (coded as 1) to "a great deal" (coded as 5). Higher scores indicate more perceived message effectiveness.
Time frame: The survey will take up to 20 minutes.
Reactance
The study will assess reactance using 1 item: "Say how much you disagree or agree with this statement: This message exaggerates the health effects of alcohol." Response options will range from "strongly disagree" (coded as 1) to "strongly agree" (coded as 5). Higher scores indicate more reactance.
Time frame: The survey will take up to 20 minutes.
Documents are hosted by the registry — open the source record to download them.
Plan to share: Yes — Investigators will post de-identified individual participant data in a publicly available repository.
Supporting information: Sap, Analytic code
This study is completed, as verified in Feb 2024. You cannot join it, but the record below documents what was studied.
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