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CompletedNCT06148350Updated Nov 28, 2023

Frenkel's Exercises for Sub-Acute Ischemic Stroke Patients

An interventional study of Stroke Rehabilitation in Stroke, Ischemic, sponsored by Al- Shifa Physiotherapy Institute /Clinic. Completed at 1 site in Pakistan. Open to participants aged 35 Years to 75 Years. Per ClinicalTrials.gov, last updated 2023-11-28.

Sponsored by Al- Shifa Physiotherapy Institute /Clinic · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 2 years 8 months after the study started (first participant enrolled Mar 2021, registered Nov 2023).
Phase
Not applicable
Study type
Interventional
Enrollment
50
Allocation
Randomized
Ages
35 Years to 75 Years
Sex
All
01

Study summary

This single-blinded, randomized controlled was aimed to compare the efficacy of Frenkel's and Conventional Balance Exercises in improving balance and quality of life in patients with subacute ischemic stroke. The participants of Group A received 'Frenkel's Exercises'. In contrast, Group B participants received 'Conventional Balance Exercise' interventions three days/week for 30-60 minutes for four weeks. The data was collected pre and post-treatment on the Berg Balance Scale and Stroke Specific-Quality of Life.

02

Conditions studied

  • Stroke, Ischemic

Keywords

  • Stroke
  • Disability
  • Exercise
  • Balance
  • Quality of Life.
03

In context

Stroke

7,286 studies on the registry are indexed under Stroke; 2,007 are open to participants now.

This study's enrollment of 50 is close to the median of 50 across 5,369 interventional studies indexed under Stroke.

Browse Stroke studies →

Lead sponsor

Al- Shifa Physiotherapy Institute /Clinic is the lead sponsor of 2 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
35 Years to 75 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  1. Patients aged between 35 to 75 years.
  2. First-ever ischemic stroke and hemiparesis within 7 to 30 days of onset.
  3. Reduced proprioception of the lower limb with a score of ≤12 on the NSA (kinesthetic and tactile sensation test),
  4. Able to comprehend tasks and follow directions with a score of ≥21 points on the Mini-Mental State Examination (MMSE).
  5. Able to independently perform standing motions for ≥1 minute.

Exclusion criteria

Exclusion Criteria:

  1. Patients with lower limb fractures within 6 months.
  2. Severe pain.
  3. Limited range of motion.
  4. Cerebellar ataxia.
  5. Medically unstable.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
50 participants (actual)

Study arms

  • Experimental
    Group A: Frenkel's Exercise

    Frenkel's exercises spanned four weeks with distinct positions: Week 1: Recumbent position, focusing on heel sliding, knee, and hip movements. Week 2: Seated exercises, emphasizing leg elevation and standing from a chair. Week 3: Erect posture activities, including forward, sideways, and backward walking with diverse steps and turns. Week 4: Comprehensive exercises across all positions, emphasizing varied movements. Each exercise set included 8-10 repetitions with 1-2 minutes of rest.

    Other: Stroke Rehabilitation

  • Active comparator
    Group B: Conventional Balance Exercises

    Structured program with 8-10 reps and 1-2 min rest: I. Strengthening: Targets hips, knees, and ankles-squats, lunges, leg presses. II. Weight-Shifting: Enhances balance with side-to-side, forward-backward steps. III. Trunk Stabilization: Improves core control-planks, crunches, twists. IV. Proprioception: Balance board exercises challenge spatial awareness, performed under physiotherapist supervision.

    Other: Stroke Rehabilitation

Interventions

  • OtherStroke Rehabilitation

    Both the groups received interventions three days/week for 30-60 minutes for four weeks

06

What researchers measure

Primary outcomes

  1. Berg Balance Scale

    The scale assesses dynamic balance skills with 14 items on a 5-point scale (0-4) and a total score of 56. It has a very high-reliability rating, with an ICC of 0.98. Participants who receive scores of 0 to 20 use wheelchairs, those who receive scores of 21 to 40 need aid or assistance, and those who receive scores of 41 or higher have independent gait.

    Time frame: Baseline

  2. Berg Balance Scale

    It has 14 items on a 5-point scale (0-4) and a total score of 56. It has a very high reliability rating, with an ICC of 0.98. Participants who receive scores of 0 to 20 use wheelchairs, those who receive scores of 21 to 40 need aid or assistance, and those who receive scores of 41 or higher have independent gait.

    Time frame: After 4-weeks

  3. Stroke-Specific Quality of Life Scale

    The scale measures the quality of life of participants. There are 49 items on the 5-point scale, with the lowest score being 49 and the highest being 245. The higher the quality of life, the lower the score. A Cronbach's alpha of 0.80 was reported as the test's reliability.

    Time frame: Baseline

  4. Stroke-Specific Quality of Life Scale

    The scale measures the quality of life of participants. There are 49 items on the 5-point scale, with the lowest score being 49 and the highest being 245. The higher the quality of life, the lower the score. A Cronbach's alpha of 0.80 was reported as the test's reliability.

    Time frame: After 4-weeks

07

Study locations

1 site
  • Al-Shifa Physiotherapy Clinic Qasimabad Hyderabad
    Karachi, Sindh, Pakistan
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 28, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06148350
Lead sponsor
Al- Shifa Physiotherapy Institute /Clinic
Responsible party
Muhammad Faisal (Mr. Muhammad Faisal, Al- Shifa Physiotherapy Institute /Clinic) — Principal investigator
First posted
Nov 28, 2023
Start date
Mar 5, 2021
Primary completion
Aug 30, 2021
Completion
Oct 5, 2021
Last update
Nov 28, 2023

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Nov 2023. You cannot join it, but the record below documents what was studied.

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