An interventional study of Thoracoscopy procedure and Chest tube thoracostomy in Empyema, sponsored by Hend Mohamed Sayed Mohamed. Not yet recruiting. Open to participants aged 18 Years to 70 Years. Per ClinicalTrials.gov, last updated 2023-11-15.
Sponsored by Hend Mohamed Sayed Mohamed · Not applicable, Interventional, and Treatment
To evaluate the efficacy of drainage achieved by thoracoscopy vs tube drainage alone.
To compare clinical outcomes such as length of hospital stay, need for additional procedures, and treatment failure rates between the two drainage methods.
To asses resolution of pleural infection and rates of fluid re-accumulation over follow-up.
To compare safety profiles and complication rates of thoracoscopy versus tube drainage alone
Empyema is a serious infection characterized by pus accumulation in the pleural space. Effective drainage and treatment is necessary for resolution. Traditionally, intercostal tube placement was standard initial management. However, recent studies have compared outcomes of early medical thoracoscopy or video-assisted thoracoscopic surgery (VATS).
Thoracoscopy enables direct visualization for thorough pleural space cleansing and debridement under direct vision. medical thoracoscopy significantly improved drainage adequacy and reduced treatment failure risks compared to tube drainage alone. Also reported shorter hospital stays and lower complication rates with early thoracoscopy-directed management.
Additional benefits of thoracoscopy include enabling talc pleurodesis for reducing empyema recurrence. thoracoscopy-directed pleurodesis achieved higher long-term success rates than tube drainage followed by pleurodesis. Overall, current evidence indicates medical thoracoscopy provides superior empyema treatment outcomes to conventional tube drainage through optimized drainage and debridement under direct visualization.
38 studies on the registry are indexed under Empyema; 11 are open to participants now.
This study's planned enrollment of 100 is close to the median of 92 across 28 interventional studies indexed under Empyema.
Browse Empyema studies →This is the only study on the registry with Hend Mohamed Sayed Mohamed as lead sponsor.
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Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
A weakened immune system. It can come from an illness, such as HIV or some blood cancers, or from medicines that turn the immune system down, for example after an organ transplant or for an autoimmune disease; steroids at higher doses count.
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A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Immunosuppression
A weakened immune system. It can come from an illness, such as HIV or some blood cancers, or from medicines that turn the immune system down, for example after an organ transplant or for an autoimmune disease; steroids at higher doses count.
Read whether the line is about a condition or about medicines, and which medicines and doses it means.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Medical thoracoscopy is a minimally invasive endoscopic procedure utilized by pulmonologists to evaluate, diagnose, and treat pleural pathologies of the lung, mainly pleural effusions.
Procedure: Thoracoscopy procedure · Procedure: Chest tube thoracostomy
Intercostal chest tube placed without thoracoscopy for patients with confirmed empyema.
Procedure: Thoracoscopy procedure · Procedure: Chest tube thoracostomy
is a minimally invasive endoscopic procedure utilized by pulmonologists to evaluate, diagnose, and treat pleural pathologies of the lung, mainly pleural effusions.
Insert chest intercostal tube without thoracoscopy
Treatment success:
Asses by chest ultrasound
Time frame: baseline
Success of pleurodesis
measured by assessing the recurrence rate of pleural effusion over a specified follow-up period.
Time frame: baseline
No study locations are listed for this record.
This study is not yet recruiting, as verified in Nov 2023. You cannot join it, but the record below documents what was studied.
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