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CompletedNCT06131619Updated Mar 20, 2024

The Role of DLOTCA-G in the Cognitive Function Evaluation of Parkinson's Patients

An observational study in Parkinson Disease, sponsored by Kutahya Health Sciences University. Completed at 1 site in Turkey. Open to participants aged 65 Years to 90 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-03-20.

Sponsored by Kutahya Health Sciences University · Observational

Study type
Observational
Model
Case-control
Time perspective
Prospective
Enrollment
90
Ages
65 Years to 90 Years
Sex
All
01

Study summary

The purpose of this study is to evaluate the usefulness of Dynamic Loewenstein's Occupational Therapy and Cognitive Assessment Scale for Geriatrics (DLOTCA-G) in parkinson patients.

Read the detailed description

The purpose of this study to evaluate the usefulness of Dynamic Loewenstein's Occupational Therapy and Cognitive Assessment Scale for Geriatrics (DLOTCA-G) in the early detection of cognitive impairment in parkinson patients aged 65 and over, with and without dementia.The investigators also aimed to compare the Mini Mental State Assessment Test with DLOTCA-G.

02

Conditions studied

  • Parkinson Disease

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Keywords

  • Parkinson Disease
  • DLOTCA-G
03

In context

Parkinson Disease

4,487 studies on the registry are indexed under Parkinson Disease; 1,082 are open to participants now.

This study's enrollment of 90 is close to the median of 96 across 1,057 observational studies indexed under Parkinson Disease.

Browse Parkinson Disease studies →

Lead sponsor

Kutahya Health Sciences University is the lead sponsor of 209 studies on the registry; 46 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
65 Years to 90 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Probability sample

Study population

Parkinson's dissease patients

Eligibility criteria

Inclusıon Criteria

  • Parkinson's patients aged 65 years and older with and without cognitive impairment (60 patients) and healthy control patients (30 patients)
  • Hoehnn Yahr Staging between 1 and 2.5 in patients with Parkinson's diseas
  • Confirmed by brain MRI from patients without vascular dementia who routinely attend the Parkinson's follow-up outpatient clinic
  • At least primary school graduates
  • In patients with Parkinson's dissease patients with cognitive impairment, MMSE below 20 in primary school education level; below 24 in secondary, high school and university education level
  • In patients with Parkinson's disease without cognitive impairment, MMSE 20 and above in primary school education level; 24 and above in secondary, high school and university education level Exclusıon Criteria
  • Preexisting cognitive impairment
  • Psychiatric disorders such as psychotic disorders, mood disorders, alcohol or drug abuse
  • Severe language dysfunction and/or bilateral limb motor dysfunction and inability to participate in clinical psychology tests, severe visual and/or auditory impairments
  • Patients with significant cerebral atrophy or neurological vascular lesions
  • The Geriatric Depression Scale was administered to all participants, and participants with a total score of 13 or more out of 30 points were excluded from the study.
05

Study design

Observational model
Case-control
Time perspective
Prospective
Enrollment
90 participants (actual)
Patient registry
No

Groups and cohorts

  • Experimental

    Parkinson's disease patients with cognitive impairment

    Other: assesment of cognitive parameters with DLOTCA-G

  • Active Comparator

    Parkinson's disease patients without cognıtıve impairment

    Other: assesment of cognitive parameters with DLOTCA-G

  • other

    Health geriatric persons

    Other: assesment of cognitive parameters with DLOTCA-G

Interventions

  • Otherassesment of cognitive parameters with DLOTCA-G

    All three groups were evaluated once with the DLOTCA-G, a cognitive assessment battery.

06

What researchers measure

Primary outcomes

  1. Dynamic Lowenstein Occupational Therapy Cognitive Assessment-Geriatric Version

    The Dynamic Lowenstein Occupational Therapy Cognitive Assessment is an occupational performance measurement battery designed to assess basic cognitive skills and visual perception in adults with neurological deficits. Consists 8 subtests: orientation, awareness, visual perception, spatial perception, praxis, visuomotor construction and thinking operations and memory. All subtests of DLOTCA-G are scored between 1 - 4 points. And higher scores indicate better cognitive performance. There is no cut-off value for Parkinson's patients.

    Time frame: Baseline (First assessment)

Secondary outcomes

  1. Mini Mental State Examination

    The Mini Mental State Examination is a brief screening tool that provides a quantitative assessment of cognitive impairment and to record cognitive changes over time. It consists of five subscales: orientation, memory, attention and calculation, recall and language. In the evaluation of the test, scores below 15 indicate low cognitive level, scores between 15 and 26 indicate medium cognitive level, and scores of 26 and above indicate high cognitive level.

    Time frame: Baseline (First assessment)

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Study locations

1 site
  • Kütahya Health Sciences University
    Kütahya, 430020, Turkey
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 20, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT06131619
Lead sponsor
Kutahya Health Sciences University
Responsible party
Merve Akdeniz Leblebicier (assoc.prof dr, Kutahya Health Sciences University) — Principal investigator
First posted
Nov 14, 2023
Start date
Jun 5, 2022
Primary completion
Jan 24, 2024
Completion
Mar 17, 2024
Last update
Mar 20, 2024

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Mar 2024. You cannot join it, but the record below documents what was studied.

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