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RecruitingNCT06117527NeuroVascUpdated Dec 26, 2025

Placental Learning Model for Neurovascular Microsurgery for the Management of Intracranial Aneurysms

An observational study in Intracranial Aneurysm, sponsored by University Hospital, Strasbourg, France. Recruiting at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-12-26.

Sponsored by University Hospital, Strasbourg, France · Observational

From the registry’s dates

  • Started Jul 2020; still recruiting 6 years 3 months later.
Study type
Observational
Model
Other
Time perspective
Other
Enrollment
50
Ages
18 Years and older
Sex
All
01

Study summary

Training in microsurgical techniques for the management of intracranial aneurysms is carried out during the practical training of the DES in Neurosurgery and during the continuous training of neurosurgeons according to the indications of the patients of the department. Currently, the recent increase in indications for endovascular treatment compared to surgical indications has led to a decrease in surgical indications and in the experience of neurosurgeons. However, there are still surgical indications that are often complex situations that neurosurgeons must overcome with a specific simulation approach.

There are different simulation models for the treatment of intracranial aneurysms. The small animal (rodent) model has the disadvantage of being poorly suited to the reproduction of intracranial aneurysms (different extracranial vessel walls, too small intracerebral vessel caliber) and of being constraining to the establishment. The computerized stimulator model which has the advantage of being able to reproduce the anatomy of a patient but whose haptic sensitivity performance is difficult to reproduce for very fine movements, it is not very accessible because it is expensive. The placental model uses a fresh human placenta, the appearance of the vessels of which is very similar to those found intracerebrally, and dilations on their walls can be performed with a pediatric urinary catheter.

02

Conditions studied

  • Intracranial Aneurysm

Keywords

  • Intracranial aneurysm
  • Placental learning model
  • Neurovascular microsurgery
  • Aneurysm
03

In context

Intracranial Aneurysm

418 studies on the registry are indexed under Intracranial Aneurysm; 119 are open to participants now.

This study's planned enrollment of 50 is below the median of 200 across 191 observational studies indexed under Intracranial Aneurysm.

Browse Intracranial Aneurysm studies →

Lead sponsor

University Hospital, Strasbourg, France is the lead sponsor of 999 studies on the registry; 358 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Woman, over the age of 18, whose placenta from an adult woman, considered as surgical waste intended for incineration; with a negative infectious status verified during pregnancy follow-up

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Woman over the age of 18;
  • Placenta considered as surgical waste intended for incineration; with a negative infectious status verified during pregnancy follow-up
  • Woman who did not express her opposition, after information, to the reuse of her placenta for educational purposes to improve the practical training of future neurosurgeons.

Exclusion criteria

Exclusion criteria:

  • Subject who expressed their opposition to participating in the study
  • Subject under guardianship or curatorship
  • Subject under safeguard of justice
05

Study design

Observational model
Other
Time perspective
Other
Enrollment
50 participants (estimated)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Evaluation of the practical training of neurosurgery students

    Hands-on training will be assessed by the Brain Aneurysm Microsurgery Skills Rating Scale

    Time frame: 1 month after training students in microsurgery for brain aneurysms

07

Study locations

1 of 1 sites recruiting
  • Service de Neurochirurgie - CHU de Strasbourg - France
    Strasbourg, 67091, France
    Recruiting
    • Irène OLLIVIER, MD · Contactirene.ollivier@chru-strasbourg.fr · 33 3 88 12 76 24
    • François PROUST, MD, PhD · Sub investigator
    • Philippe CLAVERT, MD, PhD · Sub investigator
    • Olivier IRENE, MD · Principal investigator
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 26, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT06117527
Responsible party
Sponsor
First posted
Nov 7, 2023
Start date
Jul 16, 2020
Primary completion
Feb 2028 (estimated)
Completion
Feb 2028 (estimated)
Last update
Dec 26, 2025

Study contacts

Irène OLLIVIER, MD
Contact
irene.ollivier@chru-strasbourg.fr
33 3 88 12 76 24

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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